Micropump with heating elements for a pulsed operation

• US 7,118,351 B2
• Filed: 05/12/2003
• Issued: 10/10/2006
• Est. Priority Date: 05/16/2002
• Status: Expired due to Fees

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Ziegler, Tony, Harttig, Herbert, Effenhauser, Carlo
• Primary Examiner(s): Freay, Charles G.
• Application Number:
  US10/436,387
• Publication Number:
  US 20030215334A1
• Time in Patent Office: 1,247 Days
• Field of Search: 417/208
• US Class Current: 417/208
• CPC Class Codes: A61B 5/14525 using microdialysis
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: F04B 17/00 Pumps characterised by combination with, or adaptation to, specific driving engines or motors
• CPC Class Codes: F04B 19/006 Micropumps F04B43/043 and F04B43/095 take precedence
• CPC Class Codes: F04B 19/24 Pumping by heat expansion of pumped fluid

Abstract

The invention discloses a micropump having heating elements in which an essentially pulsed operation of the heating elements occurs by means of a control unit. The pulsed operation of the heating elements enables an exact control of the flow rate. With the aid of the control unit it is possible to keep the flow rate constant over a long period of days or to change the flow rate rapidly and precisely.

Claims

1. Micropump with a heating element comprising

a fluidic transport element which can be connected to a liquid reservoir and in the connected state makes a fluidic connection between the liquid reservoir and an evaporation area,

a heating element which is located in an end area of the transport element,

a control unit for controlling the healing element,

wherein the control unit controls the heating element by signals in such a manner that the heating element is alternately in a resting phase for a period T1 and in a heating phase for a period T2 and the resting phase and the heating phase alternate essentially periodically resulting in a pulsed operation of the heating element.

2. Micropump as claimed in claim 1

in which the flow rate of the micropump is determined by the length of the periods T1, T2 and by the heat output (HO) and at least one of the parameters (T1, T2, HO) can be changed by the control unit.

3. Micropump as claimed in claim 1,

in which the signal during the heating phase T2 is composed of several signals.

4. Micropump as claimed in claim 1,

in which the heating element is positioned inside the transport element.

5. Micropump as claimed in claim 1,

in which the heating element is positioned outside the transport element.

6. Micropump as claimed in claim 1,

in which the transport element is formed from individual threads which form strands.

7. Micropump as claimed in claim 1,

in which the signals of the control unit are electrical signals.

8. Micropump as claimed in claim 1,

in which the healing element is a resistance heater.

9. Micropump as claimed in claim 1,

in which at least two transport elements are present.

10. Micropump as claimed in claim 9,

in which the second transport element is fluidically connected to the first transport element and to a second liquid reservoir.

11. Micropump as claimed in claim 1,

in which at least two heating elements are present.

12. Micropump as claimed in claim 1,

in which to transport element is formed by a channel.

13. Micropump as claimed in claim 1,

in which the transport element is formed by a microporous structure.

14. Micropump as claimed in claim 1,

in which the transport elements and/or the heating elements are manufactured by microtechnical processes.

15. Micropump as claimed in claim 1,

which is connected to a liquid reservoir containing a liquid to be transported and the fluidic transport element is at least partially filled with the liquid to be transported.

16. Microdialysis system with a pump as claimed in claim 1, and a microdialysis catheter which has a microdialysis membrane across which the pump transports a liquid.

17. Microdialysis system as claimed in claim 16 with

a sensor located downstream of the microdialysis membrane for detecting one or more analytes in the liquid.

18. Ultrafiltration device having a pump as claimed in claim 1, and an ultrafiltration catheter which has an ultrafiltration membrane through which the body fluid can be drawn.

19. Ultrafiltration device as claimed in claim 18,

having a sensor located downstream of the ultrafiltration membrane for detecting one or more analytes in the body fluid.