Method of automatic evoked response sensing vector selection using evoked response waveform analysis

• US 7,123,963 B2
• Filed: 10/31/2002
• Issued: 10/17/2006
• Est. Priority Date: 10/31/2002
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Sawchuk, Robert T., Graden, David W., Heinks, Michael W.
• Primary Examiner(s): Pezzuto, Robert E.
• Assistant Examiner(s): Heller, Tammie K.
• Application Number:
  US10/284,870
• Publication Number:
  US 20040088018A1
• Time in Patent Office: 1,447 Days
• Field of Search: 607 4- 5, 607/14, 607 27- 28, 607/123, 607/148
• US Class Current: 607/27
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

A cardiac pacing device and method for automatically selecting an optimal evoked response sensing vector based on an evaluation of the evoked response signal quality are provided. Electrode switching circuitry allows selection of multiple sensing electrode vectors. Capture detection circuitry provides capture and loss of capture signal characteristics determined during a pacing threshold search to be used in determining evoked response signal quality parameters. An optimal evoked response sensing vector is selected based on evoked response signal quality parameters meeting predetermined criteria for reliable evoked response sensing.

Claims

1. A method for automatically selecting evoked response sensing electrodes, comprising:

selecting an evoked response sensing electrode pair;

delivering a sequence of test pulses including a first set of test pulses having a first pulse energy exceeding a capture threshold and a second set of test pulses having a second pulse energy less than the capture threshold;

setting a capture detection time window following each test pulse during which a signal is sensed using the selected evoked response sensing electrode pair;

determining a maximum signal amplitude of the sensed signal occurring during the capture detection window following each of the test pulses included in the first set and the second set;

determining a minimum value of the determined maximum signal amplitudes corresponding to the first set of test pulses;

determining a signal quality parameter based on the minimum value of the maximum signal amplitudes corresponding to the first set of test pulses; and

accepting the selected evoked response sensing electrode pair in response to the signal quality parameter.

2. The method of claim 1 wherein determining the signal quality parameter includes determining a ratio of the minimum value of the maximum signal amplitudes corresponding to the first set of test pulses and a predetermined first threshold.

3. The method of claim 2, further comprising:

comparing the signal quality parameter to a predetermined second threshold; and

adjusting the first threshold in response to the signal quality parameter being less than the second threshold.

4. The method of claim 1 further comprising determining a maximum value of the determined maximum signal amplitudes corresponding to the second set of test pulses.

5. The method of claim 4 wherein determining the signal quality parameter includes determining a ratio of the maximum value of the maximum signal amplitudes corresponding to the second set of test pulses and a predetermined first threshold.

6. The method of claim 5 further comprising:

comparing the signal quality parameter to a predetermined second threshold; and

adjusting the first threshold in response to the signal quality parameter being greater than the second threshold.

7. The method of claim 4 wherein determining the signal quality parameter includes determining a ratio of the minimum value of the maximum signal amplitudes corresponding to the first set of test pulses and the maximum value of the maximum signal amplitudes corresponding to the second set of test pulses.

8. The method of claim 1 wherein determining the signal quality parameter further includes determining one of:

a time corresponding to the maximum signal amplitude, and the number of signal peaks occurring during the capture detection window.

9. The method of claim 1 further comprising:

detecting capture; and

wherein determining the signal quality parameter further includes determining a capture detection time.

10. The method of claim 1 further comprising:

selecting at least one alternate sensing electrode pair,

determining a signal quality parameter for the alternate sensing electrode pair, and

selecting an optimal sensing electrode pair based on the signal quality parameter for the alternate sensing electrode pair and the signal quality parameter for the selected evoked response sensing electrode pair.

11. A system implemented in an implantable medical device, the system comprising:

means for selecting an evoked response sensing electrode pair;

a pulse generator for delivering a sequence of test pulses including a first set of test pulses having a first pulse energy exceeding a capture threshold and a second set of test pulses having a second pulse energy less than the capture threshold;

a capture detection module for receiving a signal from the selected evoked response sensing electrode pair; and

a processor for receiving a signal from the selected evoked response sensing electrode pair, determining a maximum signal amplitude of the received signal following each of the test pulses included in the first set and the second set, determining a minimum value of the determined maximum signal amplitudes corresponding to the first set of test pulses, determining a signal quality parameter based on the minimum value, and accepting the selected evoked response sensing electrode pair in response to the signal quality parameter.

12. The system of claim 11 wherein determining the signal quality parameter includes determining a ratio of the minimum value of the maximum signal amplitudes corresponding to the first set of test pulses and a predetermined first threshold.

13. The system of claim 12, wherein the processor:

compares the signal quality parameter to a predetermined second threshold; and

adjusts the first threshold in response to the signal quality parameter being less than the second threshold.

14. The system of claim 11 wherein the processor determines a maximum value of the determined maximum signal amplitudes corresponding to the second set of test pulses.

15. The system of claim 14 wherein determining the signal quality parameter includes determining a ratio of the maximum value of the maximum signal amplitudes corresponding to the second set of test pulses and a predetermined first threshold.

16. The system of claim 15 wherein the processor:

compares the signal quality parameter to a predetermined second threshold; and

adjusts the first threshold in response to the signal quality parameter being greater than the second threshold.

17. The system of claim 14 wherein determining the signal quality parameter includes determining a ratio of the minimum value of the maximum signal amplitudes corresponding to the first set of test pulses and the maximum value of the maximum signal amplitudes corresponding to the second set of test pulses.

18. The system of claim 11 wherein determining the signal quality parameter further includes determining, from the received signal in association with the first set of pulses, one of:

a time corresponding to the maximum signal amplitude of the sensed signal,

a capture detection time, and

a number of signal peaks.

19. The system of claim 11 wherein the processor determines a signal quality parameter for an alternate sensing electrode pair selected by the switching circuitry, and identities an optimal sensing electrode pair in response to the determined signal quality parameter for the alternate sensing electrode pair and the signal quality parameter for the selected evoked response sensing electrode pair.

20. A computer readable medium for storing a set of instructions which when implemented in an implantable medical device system cause the system to:

select an evoked response sensing electrode pair;

deliver a sequence of test pulses including a first set of test pulses having a first pulse energy exceeding a capture threshold and a second set of test pulses having a second pulse energy less than the capture threshold;

set a capture detection time window following each test pulse during which a signal is sensed using the selected evoked response sensing electrode pair;

determine a maximum signal amplitude of the sensed signal occurring during the capture detection window following each test pulse;

determine a minimum value of the determined maximum signal amplitudes corresponding to the first set of test pulses;

determine a signal quality parameter based on the minimum value of the determined maximum signal amplitudes corresponding to the first set of test pulses; and

accept the selected evoked response sensing electrode pair in response to the signal quality parameter.

21. The computer readable medium of claim 20 further comprising instructions which cause the system to:

select at least one alternate sensing electrode pair,

determine a signal quality parameter for the alternate sensing electrode pair,

and select an optimal sensing electrode pair based on the signal quality parameter for the alternate sensing electrode pair and the signal quality parameter for the selected evoked response sensing electrode pair.

22. The computer readable medium of claim 20 further comprising instructions which cause the system to:

detect capture;

and wherein determining the signal quality parameter includes determining, from the signal sensed during the capture detection time window corresponding to the first set of pulses, one of a time of maximum signal amplitude, a time of capture detection, and a number of signal peaks.

23. The computer readable medium of claim 20 further comprising instructions which cause the system to determine a maximum value of the maximum signal amplitudes corresponding to the second set of test pulses and wherein the instructions for determining the signal quality parameter include instructions for determining the signal quality parameter based the maximum value.