Injection systems

• US 7,150,409 B2
• Filed: 11/30/2001
• Issued: 12/19/2006
• Est. Priority Date: 11/30/2000
• Status: Expired due to Fees

• Current Assignee: Valeritas, LLC
• Original Assignee: Biovail Laboratories Incorporated (Bausch Health Cos., Inc.)
• Inventors: Nishtala, Vasu, Lipson, David, Gonnelli, Robert R., Dimeglio, Ciro
• Primary Examiner(s): Scherbel, David A.
• Assistant Examiner(s): HOGAN, JAMES SEAN
• Application Number:
  US10/007,061
• Publication Number:
  US 20020161329A1
• Time in Patent Office: 1,845 Days
• Field of Search: 239/8, 239 86- 89, 239/525, 604/64, 604/68, 604/69, 604/82, 604/146, 604/191, 604/223, 604/70, 102/430, 102/443
• US Class Current: 239/1
• CPC Class Codes: A61M 5/2046 Media being expelled from injector by gas generation, e.g. explosive charge
• CPC Class Codes: A61M 5/2066 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/2459 upon internal pressure increase, e.g. pierced or burst A61M5/2429 takes precedence
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion
• CPC Class Codes: A61M 5/484 Regulating injection pressure

Abstract

The invention in general relates to various injection systems and devices that can be used, for example, in needleless injection systems for human, and for domestic and farm animals. In certain embodiments, the invention provides an injection device comprising: an injector defining a first cavity and an orifice; a movable member in the first cavity; a housing defining a second cavity proximal of the movable member; and a charge in the second cavity, the charge comprising at least two discrete materials.

Claims

1. An injection device comprising:

an injector defining a first cavity and an orifice;

a movable member in the first cavity;

a housing defining a second cavity proximal of the movable member;

and a charge in the second cavity, the charge comprising at least two propellants, or at least one propellant and at least one passive decay material, wherein the ignition of the charge produces a multi-stage reaction comprising ignition of the at least two propellants or ignition of the at least one propellants and at least one passive decay material in any predestined order.

2. The device of claim 1, wherein the at least two propellants, or at least one propellant and at least one passive decay material, have different combustion characteristics.

3. The device of claim 1, wherein the charge comprises at least two layers of materials.

4. The device of claim 3, wherein the at least two layers are adjacent each other.

5. The device of claim 1, wherein the charge comprises at least one trigger.

6. The device of claim 1, further comprising an electrically conductive member at least partially extending across the charge.

7. The device of claim 1, wherein the movable member and the housing are integrally formed.

8. The device of claim 1, wherein the device is configured for needleless injection.

9. The device of claim 1, wherein the device comprises a needleless injector.

10. The device of claim 1, wherein the charge is electrically activated.

11. A method of ejecting a fluid from a cavity in an injector comprising:

providing an injector defining a first cavity and an orifice;

a movable member in the first cavity;

a housing defining a second cavity proximal of the movable member, and a charge in the second cavity, the charge comprising at least two propellants or at least one propellant and at least one passive decay material, that when ignited, produce a multi-stage reaction, and

igniting the charge'"'"'s at least two propellants or at least one propellant and at least one passive decay material in any predestined order so that a fluid in the first cavity is ejected out of the cavity.

12. The method of claim 11, wherein the injector orifice is configured for needleless injection.

13. The method of claim 11, wherein the injector comprises a needleless injector.

14. The method of claim 11, further comprising selecting the at least two propellants or at least one propellant and at least one passive decay material so that the fluid is ejected from the first cavity in a predetermined fashion.

15. The method of claim 11, wherein the charge comprises at least one trigger.