Medicament dispenser

• US 7,151,456 B2
• Filed: 02/21/2001
• Issued: 12/19/2006
• Est. Priority Date: 02/26/2000
• Status: Expired due to Term

• Current Assignee: Glaxo Group Limited (Glaxosmithkline Holdings Ltd.)
• Original Assignee: Glaxo Group Limited (Glaxosmithkline Holdings Ltd.)
• Inventors: Godfrey, James William
• Primary Examiner(s): MULLEN, THOMAS J
• Application Number:
  US10/204,843
• Publication Number:
  US 20030011476A1
• Time in Patent Office: 2,127 Days
• Field of Search: 340/573.1, 340/572.7, 340/693.5, 340/540, 340/505, 340/10.1, 340/572.8, 128/203.12, 128/200.14, 604/890.1, 604/48, 604/57, 604/58, 604/403, 604/404, 604/407, 604/416, 705/2, 705/3, 705/28
• US Class Current: 340/573.1
• CPC Class Codes: A61J 2205/10 Bar codes
• CPC Class Codes: A61J 2205/30 Printed labels
• CPC Class Codes: A61J 2205/60 using magnetic or electronic identifications, e.g. chips, RFID, electronic tags
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/60 with identification means
• CPC Class Codes: G06K 19/07758 arrangements for adhering the record carrier to further objects or living beings, functioning as an identification tag
• CPC Class Codes: G16H 20/13 delivered from dispensers

Abstract

A medicament dispenser comprising a housing; a medicament container; a dispensing mechanism for dispensing medicament from the medicament container; and a radiofrequency identifier connecting to the housing or the medicament container, in the form of a radiofrequency identification tag comprising: an antenna for transmitting or receiving radiofrequency energy originating from an external remote reader; and an integrated circuit chip connecting with the antenna. The dispensing mechanism may, for example, comprise a valve, with or without a metering chamber, for dispensing aerosol formulations of medicaments, or opening or peeling mechanisms for blister strips or packs for dispensing dry powder medicaments.

Claims

1. An inhalation device for dispensing a medicament comprising

a housing;

a medicament container;

a dispensing mechanism for dispensing medicament from the medicament container; and

connecting to said housing or to said medicament container, a radiofrequency identifier, in the form of a passive radiofrequency identification tag comprising;

an antenna for receiving radiofrequency energy originating from an external remote reader and returning data to said reader; and

an integrated circuit chip connecting with said antenna.

2. An inhalation device according to claim 1, wherein the antenna is capable of receiving radiofrequency energy having a frequency of from 100 KHz to 2.5 GHz.

3. An inhalation device according to claim 2, wherein the antenna is adapted to receive radiofrequency energy having a frequency of 125 KHz.

4. An inhalation device according to claim 2, wherein the antenna is adapted to receive radiofrequency energy having a frequency of 13.56 MHz.

5. An inhalation device according to claim 2, wherein the antenna is adapted to receive radiofrequency energy having a frequency of 2.4 GHz.

6. An inhalation device according to claim 1, wherein the radiofrequency identifier is on a carrier and the carrier is mountable on the housing or the medicament container.

7. An inhalation device according to claim 6, wherein the carrier is a flexible label.

8. An inhalation device according to claim 6, wherein the carrier is a rigid disc.

9. An inhalation device according to claim 6, wherein the carrier is a rectangular block.

10. An inhalation device according to claim 6, wherein the carrier is mouldable to the medicament container or housing.

11. An inhalation device according to claim 6, wherein the carrier encases the radiofrequency identifier.

12. An inhalation device according to claim 11, wherein the carrier forms a hermetic seal for the radiofrequency identifier.

13. An inhalation device according to claim 6, wherein the carrier comprises an insulating material.

14. An inhalation device according to claim 13, wherein the insulating material comprises a glass material, paper material or organic polymeric material.

15. An inhalation device according to claim 13, wherein the carrier comprises a ferrite material.

16. An inhalation device according to claim 1, wherein the integrated circuit chip has a read only memory area.

17. An inhalation device according to claim 16, wherein the integrated circuit chip has plural memory areas thereon.

18. An inhalation device according to claim 16, wherein said integrated circuit chip comprises memory containing data in encrypted form.

19. An inhalation device according to claim 1, wherein the integrated circuit chip has a write only memory area.

20. An inhalation device according to claim 1, wherein the integrated circuit chip has a read/write memory area.

21. An inhalation device according to claim 1, wherein the integrated circuit chip has a one-time programmable memory area.

22. An inhalation device according to claim 21, wherein the one time programmable memory area contains a unique serial number.

23. An inhalation device according to claim 1, wherein the integrated circuit chip has a preset memory area containing a non-changeable data item.

24. An inhalation device according to claim 1, wherein said integrated circuit chip comprises a memory area and said memory area is password protected.

25. An inhalation device according to claim 1,

wherein the integrated circuit chip has plural memory areas thereon including

(a) a read only memory area containing a unique serial number;

(b) a read/write memory area which can be made read only; and

(c) a password protected memory area containing data in encrypted form.

26. An inhalation device according to claim 1, wherein said medicament container is an aerosol container.

27. An inhalation device according to claim 26, wherein said aerosol container comprises a suspension of a medicament in a propellant.

28. An inhalation device according to claim 27, wherein, said propellant comprises liquefied hydrofluoroalkane (“

HFA”

) 134a, HFA-227 or carbon dioxide.

29. An inhalation device according to claim 28, wherein said aerosol container comprises a solution of a medicament in a solvent.

30. An inhalation device according to claim 27, wherein the medicament is selected from the group consisting of albuterol, salmeterol, fluticasone propionate, beclomethasone dipropionate, salts or solvates thereof and any mixtures thereof.

31. An inhalation device according to claim 1, wherein said medicament container is a dry-powder container.

32. An inhalation device according to claim 31, wherein said dry-powder container comprises medicament and optionally excipient in dry-powder form.

33. An inhalation device according to claim 1, wherein the housing comprises a mouthpiece for inhalation of medicament from the medicament container therethrough.

34. A system for dispensing medicament comprising an inhalation device according to claim 1;

and

a remote external reader for reading data from the radiofrequency identifier by transmitting radiofrequency energy thereto and receiving data therefrom.

35. A system according to claim 34 wherein said reader is capable of reading individual and multiple radiofrequency identifiers simultaneously by differentiating between individual radiofrequency identifiers within the same antenna field.

36. A system according to claim 34, wherein said reader additionally comprises an electronic data management system with input/output capability comprising

a memory for storage of data;

a microprocessor for performing operations on said data; and

a signal output for outputting a signal relating to the data or the outcome of an operation on the data.

37. A system according to claim 36, additionally comprising a communicator for wireless communication with a gateway to a network computer system to enable transfer of data between the network computer system and the electronic data management system.

38. A system according to claim 37, wherein the communicator enables two-way transfer of data between the network computer system and the electronic data management system.

39. A system according to claim 37, wherein the data are communicable between the network computer system and the electronic data management system in encrypted form.

40. A system according to claim 37, wherein the communicator communicates directly with the gateway.

41. A system according to claim 37, wherein the network computer system comprises a public access network computer system.

42. A system according to claim 37, wherein the network computer system comprises a private access network computer system and the gateway is a secure gateway.

43. A system according to claim 37, wherein the communicator enables communication with a user-specific network address in the network computer system.

44. A system according to claim 43, wherein the user-specific network address is selected from the group consisting of a web-site address, an e-mail address, a file transfer protocol address and a data transfer protocol address.

45. A system according to claim 37, additionally comprising a data input system for user input of data to the electronic data management system.

46. A system according to claim 45, wherein said data input system comprises a man machine interface (MMI).

47. A system according to claim 36, additionally comprising a display for display of data from the electronic data management system to the user.

48. An inhalation device according to claim 1, wherein the integrated circuit chip has a memory area containing data indicating that a predetermined process step relating to the dispenser inhalation device has occurred.

49. An inhalation device according to claim 48, wherein the pre-determined process step is a manufacturing and/or distribution process step of the inhalation device.

50. An inhalation device according to claim 49, wherein the data indicating that a pre-determined process step relating to the inhalation device has occurred is written to the memory during the manufacturing and/or distribution process.

51. An inhalation device according to claim 50, wherein the data indicating that a pre-determined process step relating to the inhalation device has occurred comprises a time stamp.