System and methods for detection and identification of chemical substances

• US 7,154,102 B2
• Filed: 02/24/2004
• Issued: 12/26/2006
• Est. Priority Date: 11/21/2002
• Status: Expired due to Fees

• Current Assignee: CDEX Incorporated
• Original Assignee: CDEX Incorporated
• Inventors: Shriver, Timothy D., Marsteller, Laurence, Poteet, Wade Martin
• Primary Examiner(s): Porta, David
• Assistant Examiner(s): VU, MINDY D
• Application Number:
  US10/784,889
• Publication Number:
  US 20050077476A1
• Time in Patent Office: 1,036 Days
• Field of Search: 250/372
• US Class Current: 250/372
• CPC Class Codes: G01N 2021/6417 Spectrofluorimetric devices
• CPC Class Codes: G01N 21/64 Fluorescence; Phosphorescence
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients

Abstract

The invention provides a system and method utilizing, among other things, fluorescence spectroscopy in the ultraviolet portion of the electromagnetic spectrum to determine chemical species and concentrations. The basic measuring system includes optics, a spectrograph, a detector, and an energy source (“head” components), along with a computer and control electronics and power source capable of generating and detecting unique fluorescence signatures for individual and unique mixtures of chemical substances including, for example, prescribed and/or compounded medications, alcohol products, food types, synthetic drugs, narcotics, perfumes, liquids, and the like.

Claims

1. A system for verifying the composition of chemical substances comprising:

an ultraviolet fluorescence detector;

a processor coupled to the ultraviolet fluorescence detector, the processor receiving spectral data from the ultraviolet fluorescence detector; and

a database including predetermined signature data for a plurality of chemical substances,

wherein the plurality of chemical substances comprises at least one of a drug, a medication, a compounded medication, a compounded chemical formulation, a controlled substance, a narcotic, an illegal drug, an alcohol, a food product and a perfume.

2. The system according to claim 1, wherein the ultraviolet fluorescence detector includes:

an excitation light source;

a sample receiving platform capable of receiving excitation light from said excitation light source;

an ultraviolet light detector for receiving induced fluorescent energy; and

an analysis module for matching said induced fluorescent ultraviolet energy against a previously determined signature spectrum.

3. The system according to claim 1, wherein the signature data includes data for at least one of a drug, a medication, a compounded medication, a compounded chemical formulation, a controlled substance, a narcotic, an illegal drug, an alcohol, a food product and a perfume.

4. A method for verifying the composition of at least one chemical substance, comprising the steps of:

measuring induced fluorescent energy of at least one chemical substance;

accessing a database of predetermined fluorescent signatures of chemical substances; and

comparing the measured induced fluorescence energy of said at least one chemical substance against the predetermined fluorescent signatures of said accessed database of a plurality of chemical substances,

wherein the plurality of chemical substances comprises at least one of a drug, a medication, a compounded medication, a compounded chemical formulation, a controlled substance, a narcotic, an illegal drug, an alcohol, a food product and a perfume.

5. The method for verifying the composition of at least one chemical substance of claim 4, wherein said step of measuring induced fluorescent energy of said at least one chemical substance includes scanning said at least one chemical substance.

6. The method for verifying the composition of at least one chemical substance of claim 4, further comprising at least one of the steps of:

measuring said at least one chemical substance with a fluorescence inducing device;

measuring said at least one chemical substance when said chemical substance is being manufactured;

measuring said at least one chemical substance before said at least one chemical substance is packaged;

measuring said at least one chemical substance after said at least one chemical substance has been packaged;

measuring said at least one chemical substance when said at least one chemical substance is received at a distribution point;

measuring said at least one chemical substance when said at least one chemical substance is dispensed from a distribution point;

measuring said at least one chemical substance before said at least one chemical substance is administered;

measuring said at least one chemical substance before said at least one chemical substance is consumed; and

measuring said at least one chemical substance before said at least one chemical substance is disposed.

7. The method for verifying the composition of at least one chemical substance of claim 4, further comprising at least one of the steps of:

storing said measured induced fluorescent energy of said chemical;

updating a database;

updating a record;

updating a billing system;

updating a tracking system;

verifying the identity of said at least one chemical substance;

verifying the purity of said at least one chemical substance;

performing a quality control procedure;

analyzing raw materials prior to manufacturing said at least one chemical substance;

identifying the presence of an impurity;

identifying an impurity;

identifying a patient;

identifying a patient'"'"'s medication profile;

comparing said at least one chemical substance against a patient'"'"'s medication profile; and

identifying at least one unknown chemical substance.

8. The method for verifying the composition of at least one chemical substance of claim 4, further comprising at least one of the steps of:

alerting a user to an error;

alerting a user to a potential chemical interaction;

alerting a user to an impurity;

alerting a user to a unmatched fluorescent signature for said at least one chemical substance; and

alerting a user to an inaccurate concentration of said at least one chemical substance.

9. The method for verifying the composition of at least one chemical substance of claim 4, wherein said system is included in a quality control program.

10. The method for verifying the composition of at least one chemical substance of claim 4, wherein said system is included in a chemical substance dispensation protocol.

11. The method for verifying the composition of at least one chemical substance of claim 4, wherein said system is included in a chemical substance administration protocol.

12. The method for verifying the composition of at least one chemical substance of claim 4, wherein said system is included in a chemical substance disposal protocol.

13. The method for verifying the composition of at least one chemical substance of claim 4, wherein said system is included in a law enforcement protocol.

14. The method for verifying the composition of at least one chemical substance of claim 4, wherein said at least one chemical substance is at least one of a drug, a medication, a compounded medication, a compounded chemical formulation, a controlled substance, a narcotic, an illegal drug, an alcohol a food product and a perfume.