Fluorescence energy transfer probes with stabilized conformations
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Abstract
The present invention provides a class of Conformationally Assisted Probes comprising (a) a nucleic acid moiety; (b) an energy donor moiety; (c) an energy acceptor moiety; and (d) one or more stabilizing moieties.
70 Citations
12 Claims
- 1. A probe nucleic acid having the formula:
- 8. A probe nucleic acid having the formula:
Specification