Vascular testing system

• US 7,166,076 B2
• Filed: 09/07/2004
• Issued: 01/23/2007
• Est. Priority Date: 09/07/2004
• Status: Active Grant

• Current Assignee: Collaborative Care Diagnostics LLC
• Original Assignee: Biomedix, Inc.
• Inventors: Romans, John Alexander, Blanch, Gary Warner, Karels, Andrew Paul, Poliac, Marius, Ince, Daniel James, Siers, Michael Jerome, Glava, Victor Florin, Steaderman, Charles Fredrec, Rogers, William Lee, Grave, Ricky Lee
• Primary Examiner(s): Marmor, II; Charles A
• Assistant Examiner(s): Natnithithadha; Navin
• Application Number:
  US10/935,698
• Publication Number:
  US 20060052713A1
• Time in Patent Office: 868 Days
• Field of Search: 600/481, 600/483, 600/484, 600/485, 600/488, 600490-504
• US Class Current: 600/490
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02141 Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits A61B5/02233, A61B5/0235 take precedence
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/0235 Valves specially adapted therefor

Abstract

A vascular testing system includes a pressure applicator, a pressure source for generating fluid pressure at the pressure applicator; a variable orifice valve, and a valve control. The variable orifice valve is in fluid communication with the pressure applicator, and has an orifice size capable of dynamically changing. The valve control controls the variable orifice valve as a function of sensed pressure to produce substantially linear changes in pressure at the pressure applicator. Further, a method of vascular pressure measurement according to the present invention includes providing an applied pressure higher than a patient'"'"'s systolic blood pressure at a vascular location, substantially linearly decreasing the applied pressure at the vascular location, and dynamically detecting vascular pressure oscillations at the vascular location as the applied pressure is decreased.

Claims

1. A vascular testing system comprising:

a pressure applicator;

a pressure source for generating fluid pressure at the pressure applicator;

a variable orifice valve in fluid communication with the pressure applicator, wherein the valve has an orifice size capable of dynamically changing;

a pressure sensor operably connected between the pressure applicator and the variable orifice valve;

a valve control for controlling the variable orifice valve as a function of pressure sensed by the pressure sensor to produce substantially linear changes in pressure at the pressure applicator; and

a control device for causing the vascular testing system to determine a peak pressure oscillation amplitude as a function of pressure sensed by the pressure sensor as pressure applied by the pressure applicator is lessened, and to determine a first pressure value that corresponds to a pressure oscillation amplitude at approximately seventy-five percent (75%) of a peak pressure oscillation amplitude and at a pressure greater than a pressure value corresponding to the peak pressure oscillation amplitude, and to produce an output of the first pressure value identified as a pressure at a return of blood flow at a vascular location adjacent the pressure applicator.

2. The vascular testing system of claim 1, wherein the pressure applicator is an oscillometric pressure cuff.

3. The vascular testing system of claim 2, wherein the oscillometric pressure cuff is sized to fit on a human toe.

4. A method of vascular pressure measurement, the method comprising:

providing an applied pressure at a vascular location, wherein the applied pressure is higher than a patient'"'"'s systolic blood pressure;

substantially linearly decreasing the applied pressure at the vascular location;

dynamically detecting vascular pressure oscillations at the vascular location as the applied pressure is decreased;

determining a first pressure value corresponding to an oscillation amplitude of about seventy-five percent (75%) of a peak value of a curve approximating the vascular pressure oscillations, wherein the first pressure value is higher than a pressure value corresponding to the peak value of the curve approximating the vascular pressure oscillations;

generating an output that corresponds to the first pressure value; and

identifying the output as a return of blood flow pressure at the vascular location.

5. The method of claim 4, wherein an orifice size of a variable orifice valve is changed over time for linearly decreasing the applied pressure at the vascular location.

6. The method of claim 4, wherein the vascular location is disposed at a human toe.