Method and system for spinal cord stimulation prior to and during a medical procedure

• US 7,184,828 B2
• Filed: 11/19/2003
• Issued: 02/27/2007
• Est. Priority Date: 09/26/2000
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Keogh, James R., Jahns, Scott E., Hill, Michael R. S.
• Primary Examiner(s): LAYNO, CARL HERNANDZ
• Application Number:
  US10/716,810
• Publication Number:
  US 20040111118A1
• Time in Patent Office: 1,196 Days
• Field of Search: 607 2- 3, 607 46- 47, 607115-118
• US Class Current: 607/2
• CPC Class Codes: A61N 1/36014 External stimulators, e.g. with patch electrodes external pacemakers A61N1/3625
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/3625 External stimulators
• CPC Class Codes: A61N 1/385 Devices for inducing an abnormal cardiac function, e.g. fibrillation

Abstract

A method of performing a medical procedure, such as surgery, is provided. The spinal cord is stimulated in order to control at least one physiological function. The medical procedure is performed and stimulation of the spinal cord is stopped.

Claims

1. A method of performing a medical procedure, comprising:

accessing a spinal cord using an access method selected from the group consisting of intrathecal access, epidural access, and transcutaneous access;

stimulating the spinal cord to control at least one physiological function;

performing the medical procedure;

stopping stimulation of the spinal cord; and

delivering at least one drug during the medical procedure;

the drug selected from the group consisting of;

a beta-blocker, a cholinergic agent, a cholinesterase inhibitor, a calcium channel blocker, a sodium channel blocker, a potassium channel agent, adenosine, an adenosine receptor agonist, an adenosine deaminase inhibitor, dipyridamole, a monoamine oxidase inhibitor, digoxin, digitalis, lignocaine, a bradykinin agent, a serotoninergic agonist, an antiarrythmic agent, a cardiac glycoside, a local anesthetic, atropine, a calcium solution, an agent that promotes heart rate, an agent that promotes heart contractions, dopamine, a catecholamine, an inotrope glucagon, a hormone, forskolin, epinephrine, norepinephrine, thyroid hormone, a phosphodiesterase inhibitor, prostacyclin, prostaglandin and a methylxanthine.

2. A method of performing a medical procedure, comprising:

accessing a spinal cord using an access method selected from the group consisting of intrathecal access, epidural access, and transcutaneous access;

stimulating the spinal cord to control at least one physiological function;

performing the medical procedure;

stopping stimulation of the spinal cord; and

delivering at least one drug during the medical procedure;

the drug being naturally occurring.

3. A method of performing a medical procedure, comprising:

accessing a spinal cord using an access method selected from the group consisting of intrathecal access, epidural access, and transcutaneous access;

stimulating the spinal cord to control at least one physiological function;

performing the medical procedure;

stopping stimulation of the spinal cord; and

delivering at least one drug during the medical procedure;

the drug being chemically synthesized.

4. A system for performing a medical procedure, comprising:

a spinal stimulator to control at least one physiological function during the medical procedure;

a nerve stimulator in communication with the spinal stimulator to stimulate a nerve; and

a cardiac stimulator in communication with the spinal stimulator to stimulate a heart.

5. The system of claim 4 wherein the nerve stimulator stimulates a nerve from the group consisting of:

vagal nerve, a carotid sinus nerve, and a fat pad.

6. The system of claim 4 wherein the spinal stimulator comprises at least one electrode.

7. The system of claim 4 further comprising:

drug delivery means for delivering at least one drug during the medical procedure.

8. The system of claim 7 wherein the drug delivery means is selected from the group consisting of:

a spray, a cream, an ointment, a medicament, a pill, a patch, a catheter, a cannula, a needle and syringe, a pump, and an iontophoretic drug delivery device.

9. The system of claim 4 wherein the nerve stimulator comprises at least one electrode.

10. The system of claim 9 wherein the electrode is selected from the group consisting of:

nerve stimulation electrodes, endotracheal electrodes, endoesophageal electrodes, intravascular electrodes, transcutaneous electrodes, intracutaneous electrodes, balloon-type electrodes, basket-type electrodes, umbrella-type electrodes, tape-type electrodes, suction-type electrodes, screw-type electrodes, barb-type electrodes, bipolar electrodes, monopolar electrodes, metal electrodes, wire electrodes, patch electrodes, cuff electrodes, clip electrodes, needle electrodes and probe electrodes.

11. The system of claim 4 wherein the cardiac stimulator comprises at least one electrode.

12. The system of claim 11 wherein the electrode is selected from the group consisting of:

cardiac stimulation electrodes, clip electrodes, needle electrodes, probe electrodes, pacing electrodes, epicardial electrodes, patch electrodes, intravascular electrodes, balloon-type electrodes, basket-type electrodes, tape-type electrodes, umbrella-type electrodes, suction-type electrodes, endotracheal electrodes, endoesophageal electrodes, transcutaneous electrodes, intracutaneous electrodes, screw-type electrodes, barb-type electrodes, bipolar electrodes, monopolar electrodes, metal electrodes, wire electrodes and cuff electrodes.

13. A system for performing a medical procedure, comprising:

a spinal stimulator to control at least one physiological function during the medical procedure;

a nerve stimulator in communication with the spinal stimulator to stimulate a nerve; and

a cardiac stimulator in communication with the spinal stimulator to stimulate a heart;

the nerve stimulator stimulating a nerve from the group consisting of;

vagus nerve fibers, hypoglossal nerve fibers, phrenic nerve fibers, parasympathetic nerve fibers, and sympathetic nerve fibers.

14. A system for performing a medical procedure, comprising:

a spinal stimulator to control at least one physiological function during the medical procedure;

a nerve stimulator in communication with the spinal stimulator to stimulate a nerve; and

a cardiac stimulator in communication with the spinal stimulator to stimulate a heart;

the spinal stimulator comprising at least one electrode;

the at least one electrode selected from the group consisting of;

spinal stimulation electrodes, balloon-type electrodes, basket-type electrodes, umbrella-type electrodes, suction-type electrodes, guided catheters, guided electrodes, steerable catheters, and steerable electrodes.

15. A method of delivering a baby comprising the steps of:

stimulating the spinal cord to control at least one physiological function;

delivering the baby; and

stopping stimulation of the spinal cord;

the spinal cord being stimulated intermittently.

16. A method of delivering a baby comprising the steps of:

stimulating the spinal cord to control at least one physiological function;

delivering the baby; and

stopping stimulation of the spinal cord;

the spinal cord being stimulated intermittently and the physiological function being pain.

17. A stimulation device comprising:

a processor;

a nerve stimulation electrode, the nerve stimulation electrode operatively connected to the processor; and

a spinal stimulation electrode operatively connected to the processor, wherein the processor processes output from the nerve stimulation electrode and adjusts output from the spinal stimulation electrode based on output from the nerve stimulation electrode.

18. The device of claim 17 wherein the nerve stimulation electrode is selected from the group consisting of:

endotracheal electrodes, endoesophageal electrodes, intravascular electrodes, transcutaneous electrodes, intracutaneous electrodes, balloon-type electrodes, basket-type electrodes, umbrella-type electrodes, tape-type electrodes, suction-type electrodes, screw-type electrodes, barb-type electrodes, bipolar electrodes, monopolar electrodes, metal electrodes, wire electrodes, patch electrodes, cuff electrodes, clip electrodes, needle electrodes, probe electrodes, guided catheter electrodes, guided electrodes, steerable catheter electrodes, and steerable electrodes.

19. The device of claim 17 wherein the spinal stimulation electrode is selected from the group consisting of:

balloon-type electrodes, basket-type electrodes, umbrella-type electrodes, suction-type electrodes, guided catheter electrodes, guided electrodes, steerable catheter electrodes, steerable electrodes, bipolar electrodes, monopolar electrodes, metal electrodes, wire electrodes, needle electrodes, and probe electrodes.

20. The device of claim 17 further comprising:

a cardiac stimulation electrode operatively connected to the processor, wherein the processor processes output from the nerve stimulation electrode and adjusts output from the cardiac stimulation electrode based on output from the nerve stimulation electrode.

21. The device of claim 20 wherein the cardiac stimulation electrode is selected from the group consisting of:

clip electrodes, needle electrodes, probe electrodes, pacing electrodes,

epicardial electrodes, patch electrodes, intravascular electrodes, balloon-type electrodes, basket-type electrodes, tape-type electrodes, umbrella-type electrodes, suction-type electrodes, endotracheal electrodes, endoesophageal electrodes, transcutaneous electrodes, intracutaneous electrodes, screw-type electrodes, barb-type electrodes, bipolar electrodes, monopolar electrodes, metal electrodes, wire electrodes, cuff electrodes, guided catheter electrodes, guided electrodes, steerable catheter electrodes, and steerable electrodes.

22. A stimulation device comprising:

a processor;

a spinal stimulation electrode, the spinal stimulation electrode operatively connected to the processor;

a cardiac stimulation electrode operatively connected to the processor, wherein the processor processes output from the spinal stimulation electrode and adjusts output from the cardiac stimulation electrode based on output from the spinal stimulation electrode; and

a nerve stimulation electrode operatively connected to the processor, wherein the processor processes output from the spinal stimulation electrode and adjusts output from the nerve stimulation electrode based on output from the spinal stimulation electrode.

23. The device of claim 22 wherein the nerve stimulation electrode is selected from the group consisting of:

endotracheal electrodes, endoesophageal electrodes, intravascular electrodes, transcutaneous electrodes, intracutaneous electrodes, balloon-type electrodes, basket-type electrodes, umbrella-type electrodes, tape-type electrodes, suction-type electrodes, screw-type electrodes, barb-type electrodes, bipolar electrodes, monopolar electrodes, metal electrodes, wire electrodes, patch electrodes, cuff electrodes, clip electrodes, needle electrodes, probe electrodes, guided catheter electrodes, guided electrodes, steerable catheter electrodes, and steerable electrodes.

24. A stimulation device comprising:

a processor;

a cardiac stimulation electrode, the cardiac stimulation electrode operatively connected to the processor;

a spinal stimulation electrode operatively connected to the processor, wherein the processor processes output from the cardiac stimulation electrode and adjusts output from the spinal stimulation electrode based on output from the cardiac stimulation electrode; and

a nerve stimulation electrode operatively connected to the processor, wherein the processor processes output from the cardiac stimulation electrode and adjusts output from the nerve stimulation electrode based on output from the cardiac stimulation electrode.

25. The device of claim 24 wherein the nerve stimulation electrode is selected from the group consisting of:

endotracheal electrodes, endoesophageal electrodes, intravascular electrodes, transcutaneous electrodes, intracutaneous electrodes, balloon-type electrodes, basket-type electrodes, umbrella-type electrodes, tape-type electrodes, suction-type electrodes, screw-type electrodes, barb-type electrodes, bipolar electrodes, monopolar electrodes, metal electrodes, wire electrodes, patch electrodes, cuff electrodes, clip electrodes, needle electrodes, probe electrodes, guided catheter electrodes, guided electrodes, steerable catheter electrodes, and steerable electrodes.

26. A method comprising:

stimulating a spinal cord to control at least one physiological function;

stimulating the heart to adjust the beating of the heart;

stopping stimulation of the spinal cord; and

delivering at least one drug, the drug being naturally occurring.

27. The method of claim 26 wherein the drug is selected from the group consisting of:

a beta-blocker, a cholinergic agent, a cholinesterase inhibitor, a calcium channel blocker, a sodium channel blocker, a potassium channel agent, adenosine, an adenosine receptor agonist, an adenosine deaminase inhibitor, dipyridamole, a monoamine oxidase inhibitor, digoxin, digitalis, lignocaine, a bradykinin agent, a serotoninergic agonist, an antiarrythmic agent, a cardiac glycoside, a local anesthetic, atropine, a calcium solution, an agent that promotes heart rate, an agent that promotes heart contractions, dopamine, a catecholamine, an inotrope glucagon, a hormone, forskolin, epinephrine, norepinephrine, thyroid hormone, a phosphodiesterase inhibitor, prostacyclin, prostaglandin and a methylxanthine.

28. A method comprising:

stimulating a spinal cord to control at least one physiological function;

stimulating the heart to adjust the beating of the heart;

stopping stimulation of the spinal cord; and

stimulating a nerve to control at least one physiological function, the at least one physiological function including a cardiac function.

29. The method of claim 28 wherein the spinal cord is accessed in an access method selected from the group consisting of:

intrathecal access, epidural access, and transcutaneous access.

30. The method of claim 28 wherein the at least one physiological function includes pain.

31. The method of claim 28 wherein the spinal cord is stimulated intermittently.

32. The method of claim 28 wherein the heart is stimulated intermittently.

33. The method of claim 28 wherein the cardiac function is adjusting the beating of the heart.

34. The method of claim 28 wherein the nerve is selected from the group consisting of:

vagus nerve fibers, hypoglossal nerve fibers, phrenic nerve fibers, parasympathetic nerve fibers, and sympathetic nerve fibers.

35. The method of claim 28 wherein the nerve is selected from the group consisting of:

vagal nerve, a carotid sinus nerve, and a fat pad.