Porous membranes for use with implantable devices

  • US 7,192,450 B2
  • Filed: 08/22/2003
  • Issued: 03/20/2007
  • Est. Priority Date: 05/21/2003
  • Status: Active Grant
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First Claim
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1. A biointerface membrane suitable for implantation in a soft tissue of an animal, the membrane comprises:

  • a first domain, wherein the first domain supports tissue ingrowth and interferes with barrier cell layer formation, wherein the first domain comprises an open cell configuration having a plurality of interconnected cavities and a solid portion, and wherein a substantial number of the interconnected cavities are greater than or equal to about 90 microns in at least one dimension; and

    a second domain, wherein the second domain allows passage of an analyte, and wherein the second domain is resistant to cellular attachment and is impermeable to cells and cell processes.

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