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High surface area substrates for microarrays and methods to make same

  • US 7,195,872 B2
  • Filed: 11/08/2002
  • Issued: 03/27/2007
  • Est. Priority Date: 11/09/2001
  • Status: Expired due to Fees
First Claim
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1. A microarray device comprising:

  • (a) a substrate having a textured surface comprising a plurality of microfeatures; and

    (b) a plurality of separate array elements,wherein each of said plurality of array elements being larger than the distance between any two adjacent microfeatures and is immobilized on said two adjacent microfeatures to form a textured array element, wherein the textured surface further comprises a plurality of microstructures, and wherein each of the plurality of microstructures are smaller in dimension than each of the plurality of microfeatures and each of the plurality of microstructures occupies a spatially discrete region within a respective microfeature.

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