Abuse resistant lysine amphetamine compounds

  • US 7,223,735 B2
  • Filed: 06/01/2004
  • Issued: 05/29/2007
  • Est. Priority Date: 05/29/2003
  • Status: Active Grant
First Claim
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1. A pharmaceutical composition comprising an unprotected prodrug and one or more pharmaceutically acceptable additives;

  • wherein said prodrug consists of L-lysine-d-amphetamine or a pharmaceutically acceptable salt thereof;

    wherein said composition is in a form suitable for oral administration;

    wherein said composition provides release of amphetamine as an active from said prodrug following oral administration; and

    wherein said prodrug has limited bioavailability of amphetamine when administered through alternative routes of administration.

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