Method for matching and registering medical image data

• US 7,224,827 B2
• Filed: 09/26/2003
• Issued: 05/29/2007
• Est. Priority Date: 09/27/2002
• Status: Expired due to Fees

• Current Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Original Assignee: Board of Trustees of the Leland Stanford Junior University (Stanford Management Co.)
• Inventors: Beaulieu, Christopher F., Napel, Sandy A., Paik, David S., Acar, Burak, Jeffrey, R. Brooke
• Primary Examiner(s): Wu; Jingge
• Assistant Examiner(s): AZARIAN, SEYED H
• Application Number:
  US10/673,089
• Publication Number:
  US 20040136584A1
• Time in Patent Office: 1,341 Days
• Field of Search: 382/128, 382/129, 382/130, 382/131, 382/132, 382/133, 382/154, 382/168, 382/203, 382/209, 382/232, 382/256, 382/260, 382/274, 382285-297, 600/407, 600/560, 434/262, 434/267, 345/420, 378/21, 378/23
• US Class Current: 382/131
• CPC Class Codes: G06T 2207/30028 Colon; Small intestine
• CPC Class Codes: G06T 3/40 Scaling of whole images or parts thereof, e.g. expanding or contracting
• CPC Class Codes: G06T 7/33 using feature-based methods
• CPC Class Codes: G06T 7/38 Registration of image sequences

Abstract

An automatic method for the registration of prone and supine computed tomographic colonography data is provided. The method improves the radiologist'"'"'s overall interpretation efficiency as well as provides a basis for combining supine/prone computer-aided detection results automatically. The method includes determining (centralized) paths or axes of the colon from which relatively stationary points of the colon are matched for both supine and prone positions. Stretching and/or shrinking of either the supine or prone path perform registration of these points. The matching and registration occurs in an iterative and recursive manner and is considered finished based on one or more decision criteria.

Claims

1. A method for matching and registering medical image data, comprising the steps of:

(a) obtaining a first image data set of a tubular structure;

(b) obtaining a second image data set of said tubular structure;

(c) determining a first path of said tubular structure in said first image;

(d) determining a second path of said tubular structure in said second image;

(e) determining landmarks in said first path;

(f) determining landmarks in said second path;

(g) matching said landmarks in said first path with said landmarks in said second path through identifying correspondence between said landmarks of said first path with said landmarks of said second path; and

(h) registering said first path to said second path through stretching or shrinking of said first path to said second path until said corresponding landmarks in said first path and said second path coincide along said respective paths.

2. The method as set forth in claim 1, wherein the step of matching comprises the step of sorting and comparing the position of said landmarks in said first path with said landmarks of said second path based on anatomical information along said respective paths.

3. The method as set forth in claim 1, wherein the step of registering comprises the step of linear stretching or shrinking.

4. The method as set forth in claim 1, wherein the step of registering comprises the step of non-linear stretching or shrinking.

5. The method as set forth in claim 1, further comprising iterative and recursive steps until one or more decision criteria are met.

6. The method as set forth in claim 1, wherein said tubular structure is a colon, blood vessel or airways.

7. The method as set forth in claim 1, wherein said first image data set is based on computed tomography colonography data from a colon in supine position and wherein said second image data set is based on computed tomography colonography data from a colon in prone position.

8. The method as set forth in claim 1, wherein said first image data set is based on computed tomography colonography data from a colon in prone position and wherein said second image data set is based on computed tomography colonography data from a colon in supine position.

9. A method for registering computed tomography colonography data obtained in a supine position and in a prone position, comprising the steps of:

(a) obtaining said computed tomography colonography data in said supine position;

(b) obtaining said computed tomography colonography data in said prone position;

(c) determining a first path in said computed tomography colonography data of said colon in said supine position;

(d) determining a second path in said computed tomography colonography data of said colon in said prone position;

(e) determining landmarks in said first path;

(f) determining landmarks in said second path; and

(g) matching said landmarks in said first path with said landmarks in said second path through identifying correspondence between said landmarks of said first path with said landmarks of said second path; and

(h) registering said first path to said second path through stretching or shrinking of said first path to said second path until said corresponding landmarks in said first path and said second path coincide along said respective paths, or registering said first path to said second path through stretching or shrinking of said second path to said first path until said corresponding landmarks in said first path and said second path coincide along said respective paths.

10. The method as set forth in claim 9, wherein the step of matching comprises the step of sorting and comparing the position of said landmarks in said first path with said landmarks of said second path based on anatomical information along their respective paths.

11. The method as set forth in claim 9, further comprising the step of linear stretching or shrinking.

12. The method as set forth in claim 9, further comprising the step of linear stretching or shrinking.

13. The method as set forth in claim 9, further comprising iterative and recursive steps until one or more decision criteria are met.