System and methods for processing analyte sensor data

  • US 7,276,029 B2
  • Filed: 08/01/2003
  • Issued: 10/02/2007
  • Est. Priority Date: 08/01/2003
  • Status: Active Grant
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1. A method for calibrating a substantially continuous analyte sensor, the method comprising:

  • receiving a data stream from an analyte sensor, including one or more sensor data points;

    receiving reference data from a reference analyte monitor, comprising one or more reference data points;

    providing at least one matched data pair by matching reference analyte data to substantially time corresponding sensor data;

    creating a conversion function based on said at least one matched data pair;

    evaluating said at least one matched data pair, including at least one of

         1) ensuring said at least one matched data pair is within a predetermined time range,

         2) ensuring said at least one matched data pair is no older than a predetermined value,

         3) ensuring said at least one matched data pair is substantially distributed with additional matched data pairs, if present, between high and low matched data pairs over a predetermined time range, and

         4) ensuring said at least one matched data pair is within a predetermined range of analyte values, wherein the step of evaluating said at least one matched data pair further comprises at least one of evaluating a rate of change of the analyte concentration, evaluating a congruence of respective sensor and reference data in a matched data pair, and evaluating physiological changes; and

    subsequently modifying said conversion function if such modification is required by said evaluation.

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