Clustering of recorded patient neurological activity to determine length of a neurological event
First Claim
1. A computer-implemented method for determining a detection cluster that is associated with a neurological event of a nervous system disorder of a patient, the detection cluster being associated with at least one detection that exceeds a predetermined threshold of a measure for a first predetermined time duration, the method comprising the steps of:
- (a) receiving a set of at least one signal;
(b) determining an onset of the neurological event based on the set of at least one signal;
(c) determining an end of a neurological event based on the set of at least one signal, wherein the determining is further based on all neurological signals of the set of the at least one signal being less than the predetermined threshold of the measure for a second predetermined time duration; and
(d) clustering a set of at least one detection between the onset and the end of the neurological event.
1 Assignment
0 Petitions
Accused Products
Abstract
Apparatus and method detect a detection cluster that is associated with a neurological event, such as a seizure, of a nervous system disorder and update therapy parameters that are associated with a treatment therapy. The occurrence of the detection cluster is detected when the maximal ratio exceeds an intensity threshold. If the maximal ratio drops below the intensity threshold for a time interval that is less than a time threshold and subsequently rises above the intensity threshold, the subsequent time duration is considered as being associated with the detection cluster rather than being associated with a different detection cluster. Consequently, treatment of the nervous system disorder during the corresponding time period is in accordance with one detection cluster. Treatment therapy may be provided by providing electrical stimulation, drug infusion or a combination. Therapy parameters may be updated for each mth successive group of applications of the treatment therapy or for each nth detection cluster.
197 Citations
23 Claims
-
1. A computer-implemented method for determining a detection cluster that is associated with a neurological event of a nervous system disorder of a patient, the detection cluster being associated with at least one detection that exceeds a predetermined threshold of a measure for a first predetermined time duration, the method comprising the steps of:
-
(a) receiving a set of at least one signal; (b) determining an onset of the neurological event based on the set of at least one signal; (c) determining an end of a neurological event based on the set of at least one signal, wherein the determining is further based on all neurological signals of the set of the at least one signal being less than the predetermined threshold of the measure for a second predetermined time duration; and (d) clustering a set of at least one detection between the onset and the end of the neurological event. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
-
12. A computer-implemented method for determining a detection cluster that is associated with a neurological event of a nervous system disorder of a patient, the detection cluster being associated with at least one detection that exceeds a predetermined threshold of a measure for a first predetermined time duration, the method comprising the steps of:
-
(a) receiving a set of at least one signal; (b) determining an onset of the neurological event based on the set of at least one signal; (c) determining an end of a neurological event based on the set of at least one signal; and (d) clustering a set of at least a first detection and a second detection between the onset and the end of the neurological event, wherein the clustering comprises; (i) determining a time interval between the first detection and the second detection, wherein the first detection and the second detection are adjacent detections; and (ii) if the time interval is less than a second predetermined duration, clustering the first and second detections.
-
-
13. An apparatus for determining a detection cluster that is associated with a neurological event of a nervous system disorder, the detection cluster being associated with at least one detection that exceeds a predetermined threshold of a measure for a first predetermined time duration, the apparatus comprising in combination:
-
a configuration of monitoring elements; and a processor that is coupled to the configuration of monitoring elements, the processor configured to perform the steps of; (a) receiving a set of at least one signal; (b) determining an onset of the neurological event based on the set of at least one signal; (c) determining an end of a neurological event based on the set of at least one signal, wherein the determining is farther based on all neurological signals of the set of at least one signal being less than the predetermined threshold for a second predetermined time duration; and (d) clustering a set of detections between the onset and the end of the neurological event. - View Dependent Claims (14, 15, 16, 17, 18)
-
-
19. An apparatus for determining a detection cluster that is associated with a neurological event of a nervous system disorder, the detection cluster being associated with at least one detection that exceeds a predetermined threshold of a measure for a first predetermined time duration, the apparatus comprising in combination:
-
a configuration of monitoring elements; and a processor that is coupled to the configuration of monitoring elements, the processor configured to perform the steps of; (a) receiving a set of at least one signal; (b) determining an onset of the neurological event based on the set of at least one signal; (c) determining an end of a neurological event based on the set of at least one signal; and (d) clustering a set of detections between the onset and the end of the neurological event, the clustering comprising; (i) determining a time interval between a first detection and a second detection, wherein the first detection and the second detection are adjacent detections; and (ii) if the time interval is less than a second predetermined duration, clustering the first and second detections.
-
-
20. An apparatus for determining a detection cluster that is associated with a neurological event of a nervous system disorder, the detection cluster being associated with at least one detection that exceeds a predetermined threshold of a measure for a first predetermined time duration, the apparatus comprising in combination:
-
a configuration of monitoring elements; and a processor that is coupled to the configuration of monitoring elements, the processor configured to perform the steps of; (a) receiving a set of at least one signal; (b) determining an onset of the neurological event based on the set of at least one signal; (c) determining an end of a neurological event based on the set of at least one signal; and (d) clustering a set of detections that includes a first detection and a second detection between the onset and the end of the neurological event.
-
-
21. A method for determining a detection cluster that is associated with a neurological event of a nervous system disorder, comprising:
-
(a) receiving a set of at least one signal; (b) determining an onset of the neurological event based on the set of at least one signal; (c) determining an end of a neurological event based on the set of at least one signal; and (d) clustering a set of detections that includes at least a first detection and a second detection between the onset and the end of the neurological event, the first detection exceeding a predetermined threshold for a predetermined period. - View Dependent Claims (22, 23)
-
Specification