Heart-activity monitoring with multi-axial audio detection

• US 7,302,290 B2
• Filed: 08/04/2004
• Issued: 11/27/2007
• Est. Priority Date: 08/06/2003
• Status: Active Grant

• Current Assignee: Inovise Medical, Inc.
• Original Assignee: Inovise Medical, Inc.
• Inventors: Bauer, Peter T.
• Primary Examiner(s): Evanisko; George R.
• Assistant Examiner(s): PATTON, AMANDA K
• Application Number:
  US10/912,676
• Publication Number:
  US 20050033190A1
• Time in Patent Office: 1,210 Days
• Field of Search: 600/513, 600/514, 600/528, 381/67
• US Class Current: 600/513
• CPC Class Codes: A61B 2562/0204 Acoustic sensors
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/25 Bioelectric electrodes therefor
• CPC Class Codes: A61B 5/6834 using vacuum
• CPC Class Codes: A61B 7/00 Instruments for auscultation

Abstract

Apparatus and associated methodology for monitoring correlatable anatomical electrical and sound signals, such as electrical and audio signals produced by human heart activity, including (a) attaching to a selected, common anatomical site ECG (or other) electrode structure, and a multi-axial sound sensor, and (b) simultaneously collecting from adjacent that site both ECG(or other)-electrical and sound signals, where such sound signals arrive adjacent the site along multiple, angularly intersecting axes.

Claims

1. Heart-activity monitor structure adapted to collect, and to deliver as output for assessment, ECG-electrical, and heart-activity-generated sound, signals/data effectively from a selected common anatomical site, said monitor structure, in operative condition, comprising

ECG electrode structure conductively attachable to a person'"'"'s anatomy adjacent an anatomical site,

a multi-axial sound sensor unitized with said electrode structure in a manner whereby, with the electrode structure so attached to the anatomy, the sensor is disposed to sense at least heart-activity-generated sounds arriving along multiple, angularly intersecting axes adjacent the selected site, and

sound-signal processing structure operatively connected to said sensor and capable of utilizing X-axis and Y-axis components of detected sound to enable position shifting of the sensor in the vicinity of the site so as to obtain a related maximum Z-axis sound component, wherein said sensor is capable of detecting sounds arriving at such a selected site along orthogonal X, Y and Z axes, where the Z axis is substantially normal to the anatomy at the location of the site.

2. The monitor structure of claim 1, wherein said electrode structure is constructed with selected bio-impedance-matching characteristics.

3. The monitor structure of claim 1 which further includes memory structure operatively connected to said electrode structure and sound sensor for capturing collected data for future reference.

4. The monitor structure of claim 1 which further includes signal processing structure operatively connected to receive and process such output, and to deliver therefrom a processed-output apexcardiogram signal.

5. The monitor structure of claim 1, wherein said electrode structure and said sensor are releasably connectable relative to one another.

6. The monitor structure of claim 1, wherein at least one of said electrode structure and said sensor is non-patient-specific and reusable.

7. The monitor structure of claim 1, wherein said sensor takes the form of multiple uni-axis accelerometers each having respective sound-collecting axes, with each of these sound-collecting axes being differently oriented relative to the other sound-collecting axes.

8. The monitor structure of claim 1, which further includes sound-signal processing structure operatively connected to said sensor and capable of utilizing X-axis and Y-axis components of detected sound to enable the minimizing of sound-signal interference derived from sources including ambient noise and non-heart-related human body sounds.

9. The monitor structure of claim 1, wherein said sensor takes the form of a multi-axis accelerometer.

10. The monitor structure of claim 9, wherein said accelerometer is a MEMS device.

11. The monitor structure of claim 10, wherein said MEMS device operates on a principle featuring, non-exclusively, at least one of capacitive, thermal, piezoelectric, and piezoresistive behavior.

12. Heart-activity monitor structure adapted to collect, and to deliver as output for assessment, at least heart-activity-generated sound signals from a selected anatomical site, said monitor structure comprising

a multi-axial sound sensor effectively attachable to such a selected anatomical site, and when so attached, operable to detect at least heart-activity-generated sounds arriving along multiple angularly intersecting axes located adjacent the selected site, and

output structure operatively connected to said sensor for outputting a signal relating to such detected sounds

wherein said multi-axial sound sensor is constructed and arranged to sense the so-called S1, S2, S3 and S4 sounds (the S-sounds), as well as murmurs, and wherein said multi-axial sound sensor includes signal processing structure operable to evaluate selected X, Y and Z sound-signal ratios in order to determine the point of maximum impact for each of such sounds.

13. The monitor structure of claim 12, wherein said sensor takes the form of a multi-axis accelerometer.

14. The monitor structure of claim 12, wherein said sensor takes the form of multiple uni-axis accelerometers each having respective sound-collecting axes, with each of these sound-collecting axes being differently oriented relative to the other sound-collecting axes.

15. The monitor structure of claim 12 which further includes filter structure responsive to detect sounds to deliver an apexcardiogram output signal.

16. The monitor structure of claim 12, wherein said sensor is capable of detecting sounds arriving at such a selected site along orthogonal X, Y and Z axes, where the Z axis is substantially normal to the anatomy of the location of the site.

17. The monitor structure of claim 16 which further includes plural directional sensors activatable, in relation to X-axis and Y-axis detected sounds, to produce a directional indication of direction on the anatomy toward which to move the sensor so as to maximize the detected Z-axis sound.

18. Methodology for monitoring correlatable ECG-electrical and audio signals produced by human heart activity comprising

attaching to a selected, common anatomical site ECG electrode structure, and a multi-axial sound sensor,

simultaneously collecting from adjacent that site both ECG-electrical and sound signals, where such sound signals arrive adjacent the site along multiple, angularly intersecting axes, and

performing signal processing utilizing collected X-axis and Y-axis sounds to accomplish (a) minimizing extraneous noise interference with desired sound signal information, and (b) offering a sense of anatomical surface directionality to guide lateral repositioning of at least the sound sensor so as to maximize the acquisition of Z-axis sound information.

19. The methodology of claim 18, wherein the axes along which sound signals are collected are X, Y and Z orthogonal axes, with the Z-axis being disposed substantially normal to the anatomy at the selected anatomical site.

20. The method of claim 18, wherein sound-signal collecting by the sound sensor is performed by the use, and stimulation of, a single multi-axis accelerometer.

21. The method of claim 18, wherein sound-signal collecting by the sound sensor is performed by the use, and stimulation of, multiple uni-axis accelerometers.

22. The method of claim 18, wherein said collecting of sound signals includes the collecting, where present, of at least one of the known S-sounds, including S1, S2, S3 and S4, as well as murmurs.

23. The method of claim 18 which further comprises performing signal processing so as to produce a processed-output apexcardiogram signal.

24. A method for monitoring anatomical-activity-produced sounds arriving at a selected anatomical site comprising

establishing at the selected site a mechanical, sound-energy-responsive drive connection between the human anatomy and a multi-axial, motion-to-electrical-signal transducer and collecting multi-axial sounds arriving at that site, wherein the sounds are related to heart activity,

wherein the axes of sound collection at the site are three in number, and are orthogonally X, Y, Z related to one another, wherein Z-axis sounds are normally oriented relative to the surface of the anatomy at the selected site, and which further includes determining the point of maximum impact of such sounds at that site, and

observing multi-axially detected electrical signal components arriving at the selected site and produced by that transducer in response to anatomy-related, sound-generated motion activities communicated through the established drive connection.

25. Methodology for monitoring audio signals produced by human heart activity comprising

attaching to a selected, common anatomical site a multi-axial sound sensor, and

collecting from adjacent that site sound signals which arrive adjacent the site along multiple, angularly intersecting axes;

processing the sound-signals utilizing X-axis and Y-axis components of a detected sound to enable position shifting of the sensor in the vicinity of the site so as to obtain a related maximum Z-axis sound component, wherein said sensor is capable of detecting sounds arriving at such a selected site along orthogonal X, Y and Z axes, where the Z axis is oriented substantially normal to the anatomy at the location of the site.

26. Heart-activity monitor structure adapted to collect cooperatively, and to deliver as output for assessment, ECG-electrical, and heart-activity-generated sound, signals/data effectively and simultaneously from a pair of selected, laterally spaced anatomical sites, said monitor structure, in operative condition, comprising

a pair of signal-collection units, each including

(a) ECG electrode structure conductively attachable to a person'"'"'s anatomy adjacent such a selected site, and

(b) an associated, multi-axial sound sensor unitized with said associated electrode structure in a manner whereby, with the electrode structure so attached to the anatomy, the sensor is disposed to sense at least heart-activity-generated sounds arriving along multiple, angularly intersecting axes adjacent the selected site,

wherein each of said signal-collection units is constructed and arranged to sense the so-called S1, S2, S3 and S4 sounds (the S-sounds), as well as murmurs, and wherein said multi-axial sound sensor includes signal processing structure operable to evaluate selected X, Y and Z sound-signal ratios in order to determine the point of maximum impact for each of such sounds.