Prosthetic valve for transluminal delivery

• US 7,329,278 B2
• Filed: 02/13/2006
• Issued: 02/12/2008
• Est. Priority Date: 11/17/1999
• Status: Expired

• Current Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Original Assignee: Corevalve Incorporated (Medtronic Plc)
• Inventors: Seguin, Jacques, Börtlein, Georg
• Primary Examiner(s): GHERBI, SUZETTE JAIME J
• Application Number:
  US11/352,614
• Publication Number:
  US 20060129235A1
• Time in Patent Office: 729 Days
• Field of Search: 623 111- 219, 623/903, 606/108, 606/194
• US Class Current: 623/2.1
• CPC Class Codes: A61B 17/0218 for minimally invasive surgery A61B17/0281, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2433 using balloon catheter
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2210/0023 operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2250/0003 having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/0069 Sealing means
• CPC Class Codes: Y10S 623/904 Heart

Abstract

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Claims

1. A method of replacing a deficient native valve comprising the steps of:

providing a prosthetic valve assembly, the assembly comprising a valve, a valve support permitting attachment thereto of the base and the commissures of the valve, and an anchor for engaging the lumen wall when expanded for preventing substantial migration of the valve assembly when positioned in place;

hooking a portion of the valve support to a catheter with at least one hook member projecting outward from an outer surface of the catheter proximal to a distal end of the catheter;

collapsing the valve support and anchor to fit within a distally positioned sheath on the catheter;

advancing the catheter to a deficient native valve;

deploying the valve; and

withdrawing the catheter, leaving the valve assembly to function in place of the deficient native valve.

2. The method of claim 1, wherein the valve support and anchor are self-expanding.

3. The method of claim 1, further comprising the step of excising the native valve.

4. The method of claim 1, wherein the excising step comprises using the same catheter used to deploy the valve assembly.

5. The method of claim 1, wherein the anchor is spaced from the valve support.

6. The method of claim 1, wherein deploying the valve assembly comprises deploying the valve assembly along an implantation site from the native valve and across a coronary artery.