Methods for drug discovery, disease treatment, and diagnosis using metabolomics

  • US 7,329,489 B2
  • Filed: 10/27/2003
  • Issued: 02/12/2008
  • Est. Priority Date: 04/14/2000
  • Status: Active Grant
First Claim
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1. A method for metabolomically identifying small molecules indicative of amyotrophic lateral sclerosis, comprising:

  • obtaining a small molecule profile from a subject suffering from amyotrophic lateral sclerosis; and

    comparing the small molecule profile from the subject to a standard small molecule profile, thereby identifying small molecules indicative of amyotrophic lateral sclerosis, wherein said small molecule profile is obtained using one or more techniques which detect 50% or more of the small molecules in said sample.

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