Biocompatible crosslinked polymers with visualization agents

  • US 7,332,566 B2
  • Filed: 12/02/2005
  • Issued: 02/19/2008
  • Est. Priority Date: 09/23/1996
  • Status: Expired due to Term
First Claim
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1. A polymeric coating for a substrate comprising:

  • water, a biocompatible visualization agent, and a biodegradable hydrogel, that is essentially completely degradable in vivo by hydrolytic degradation, with the hydrogel having an interior and an exterior, with the exterior having a substrate coating surface, and the visualization agent being at least partially disposed within the interior,wherein the hydrogel comprises chemical groups that are prone to aqueous hydrolysis and is thereby degradable in vitro by exposure to aqueous solution, andwherein the visualization agent has a predetermined concentration that indicates a predetermined thickness of the hydrogel as deposited on the substrate.

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