Closed loop system for controlling insulin infusion

  • US 7,354,420 B2
  • Filed: 05/03/2006
  • Issued: 04/08/2008
  • Est. Priority Date: 06/03/1999
  • Status: Expired due to Term
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First Claim
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1. A system for calculating the amount of liquid to be infused into a body of a user, the system comprising:

  • means for obtaining a blood glucose concentration of the user;

    means for generating a controller input based on the blood glucose concentration; and

    means for generating infusion calculations by a proportional plus, integral plus, derivative (PID) controller from the controller input using at least one preset controller gain;

    wherein the at least one preset controller gain includes at least one tuning parameter that further modifies the commands generated by the PID controller to create an insulin concentration profile that more closely resembles the insulin concentration profile that would be generated by the release of insulin by beta cells in an individual with a healthy normally functioning pancreas; and

    wherein the at least one tuning parameter is a lead/lag compensator.

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