Method and apparatus for intra-aortic substance delivery to a branch vessel
First Claim
1. A local renal infusion system for treating a renal system in a patient from a location within the abdominal aorta associated with first and second flow paths within an outer region of abdominal aortic blood flow generally along the abdominal aorta wall and into first and second renal arteries, respectively, via their corresponding first and second renal ostia along an abdominal aorta wall in the patient, comprising:
- a local injection assembly comprising a first infusion tube having a distal end, a proximal end, and a first injection port disposed between the distal end and the proximal end, a second infusion tube having a distal end, a proximal end, and a second injection port disposed between the distal end and the proximal end, and a central catheter tube with first and second injection ports;
wherein the distal end of the first infusion tube and the distal end of the second infusion tube are attached to the central catheter tube, such that when the first infusion tube and the second infusion tube are in an expanded configuration the first infusion tube and the second infusion tube bow outward away from the central catheter tube, and when the first infusion tube and the second infusion tube are in a retracted configuration the first infusion tube and the second infusion tube straighten inward toward the central catheter tube;
wherein the local injection assembly is adapted to be positioned at the location with the first and second injection ports at first and second respective positions, respectively, corresponding with the first and second flow paths;
wherein the local injection assembly is adapted to be fluidly coupled to a source of fluid agent externally of the patient when the local injection assembly is positioned at the location; and
wherein the local injection assembly is adapted to inject a volume of fluid agent from the source, through the first and second injection ports at the first and second positions, respectively, and bi-laterally into the first and second renal arteries, also respectively, via the respective corresponding first and second renal ostia without substantially altering abdominal aorta flow along the location.
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Accused Products
Abstract
A renal flow system injects a volume of fluid agent into a location within an abdominal aorta in a manner that flows bi-laterally into each of two renal arteries via their respectively spaced ostia along the abdominal aorta wall. A local injection assembly includes two injection members, each having an injection port that couples to a source of fluid agent externally of the patient. The injection ports may be positioned with an outer region of blood flow along the abdominal aorta wall perfusing the two renal arteries. A flow isolation assembly may isolate flow of the injected agent within the outer region and into the renals. The injection members are delivered to the location in a first radially collapsed condition, and bifurcate across the aorta to inject into the spaced renal ostia. A delivery catheter for upstream interventions is used as a chassis to deliver a bilateral local renal injection assembly to the location within the abdominal aorta.
320 Citations
11 Claims
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1. A local renal infusion system for treating a renal system in a patient from a location within the abdominal aorta associated with first and second flow paths within an outer region of abdominal aortic blood flow generally along the abdominal aorta wall and into first and second renal arteries, respectively, via their corresponding first and second renal ostia along an abdominal aorta wall in the patient, comprising:
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a local injection assembly comprising a first infusion tube having a distal end, a proximal end, and a first injection port disposed between the distal end and the proximal end, a second infusion tube having a distal end, a proximal end, and a second injection port disposed between the distal end and the proximal end, and a central catheter tube with first and second injection ports; wherein the distal end of the first infusion tube and the distal end of the second infusion tube are attached to the central catheter tube, such that when the first infusion tube and the second infusion tube are in an expanded configuration the first infusion tube and the second infusion tube bow outward away from the central catheter tube, and when the first infusion tube and the second infusion tube are in a retracted configuration the first infusion tube and the second infusion tube straighten inward toward the central catheter tube; wherein the local injection assembly is adapted to be positioned at the location with the first and second injection ports at first and second respective positions, respectively, corresponding with the first and second flow paths; wherein the local injection assembly is adapted to be fluidly coupled to a source of fluid agent externally of the patient when the local injection assembly is positioned at the location; and wherein the local injection assembly is adapted to inject a volume of fluid agent from the source, through the first and second injection ports at the first and second positions, respectively, and bi-laterally into the first and second renal arteries, also respectively, via the respective corresponding first and second renal ostia without substantially altering abdominal aorta flow along the location. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification