System for dispensing biological fluids

• US 7,418,981 B2
• Filed: 02/22/2007
• Issued: 09/02/2008
• Est. Priority Date: 09/02/2004
• Status: Expired due to Fees

• Current Assignee: Exscribe, Inc.
• Original Assignee: Gary A. Kirian, James W. Baker
• Inventors: Kirian, Gary A., Baker, James W.
• Primary Examiner(s): MAUST, TIMOTHY LEWIS
• Application Number:
  US11/678,005
• Publication Number:
  US 20070151984A1
• Time in Patent Office: 558 Days
• Field of Search: 141/2, 141 23- 27, 141/82, 141/144, 141319-323, 141/329, 141/330, 141/9, 141/100, 422100-104, 604403-416
• US Class Current: 141/9
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2058 having multiple connecting ports
• CPC Class Codes: A61J 1/2062 with directional valves
• CPC Class Codes: A61J 1/2089 Containers or vials which are to be joined to each other in order to mix their contents combinations of vial and syringe for mixing their contents A61J1/2096
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 39/223 Multiway valves
• CPC Class Codes: A61M 5/14216 Reciprocating piston type
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons

Abstract

Systems, including methods and apparatus, for dispensing biological fluids, such as allergens.

Claims

1. A method of dispensing biological fluid, comprising:

operating at least one cooling device to refrigerate a plurality of sealed stock vials disposed in an array in a housing, the stock vials holding biological fluids;

blowing filtered air into a compartment disposed below a stock vial disposed in the housing; and

transferring an aliquot of a biological fluid held by the stock vial, out through a resilient closure of the stock vial and into a syringe pump disposed in the compartment,

wherein the step of transferring includes a step of transferring at least a portion of the aliquot from the syringe pump to a receiver vial, through a resilient closure of the receiver vial, and

wherein the step of transferring is performed a plurality of times with aliquots of different biological fluids to form a mixture of the different biological fluids in the receiver vial.

2. The method of claim 1, wherein the step of blowing filtered air includes a step of filtering air to remove microorganisms.

3. The method of claim 2, where the step of filtering air includes a step of filtering air with a HEPA filter.

4. The method of claim 1, where the step of blowing filtered air includes a step of creating a positive pressure in the compartment with the filtered air to reduce entry of unfiltered air into the compartment.

5. The method of claim 1, wherein the stock vial is disposed in a vessel storage compartment in the housing, further comprising a step of blowing filtered air into the vessel storage compartment.

6. The method of claim 1, further comprising a step of disposing at least one stock vial in the housing such that a label and/or a fluid level of the at least one stock vial is visible from outside the housing.

7. The method of claim 6, wherein the step of disposing includes a step of disposing the at least one stock vial behind a transparent wall of the housing such that at least a portion of the at least one stock vial is visible through the transparent wall.

8. The method of claim 1, further comprising a step of disposing the stock vials in the array, with each stock vial in an inverted configuration.

9. The method of claim 1, wherein the step of transferring performed a plurality of times includes a step of transferring allergens to make an allergen mixture for an allergy patient.

10. The method of claim 1, wherein the housing is connected to a base, further comprising a step of rotating the array of stock vials relative to the base in order to select the stock vial from which the aliquot is to be transferred.

11. The method of claim 1, wherein the step of transferring includes a step of automatically operating a power-driven syringe pump.

12. The method of claim 1, further comprising a step of inputting instructions for the step of transferring to a controller that controls operation of the syringe pump.

13. The method of claim 12, wherein the step of inputting instructions includes a step of inputting instructions to the controller via a touchscreen.

14. The method of claim 1, wherein the syringe pump is a manually driven syringe.

15. The method of claim 1, wherein a distinct syringe pump is used each time the step of transferring is performed.