Modified fluorinated nucleoside analogues
DCFirst Claim
Patent Images
1. A (2′
- R)-2′
-deoxy-2′
-fluoro-2′
-C-methyl nucleoside (β
-D or β
-L) or its pharmaceutically acceptable salt of the structure;
7 Assignments
Litigations
1 Petition
Accused Products
Abstract
The disclosed invention provides compositions and methods of treating a Flaviviridae infection, including hepatitis C virus, West Nile Virus, yellow fever virus, and a rhinovirus infection in a host, including animals, and especially humans, using a (2′R)-2′-deoxy-2′-fluoro-2′-C-methyl nucleosides, or a pharmaceutically acceptable salt or prodrug thereof.
308 Citations
19 Claims
-
1. A (2′
- R)-2′
-deoxy-2′
-fluoro-2′
-C-methyl nucleoside (β
-D or β
-L) or its pharmaceutically acceptable salt of the structure;
- View Dependent Claims (2, 3, 4, 5, 7, 8, 9, 10, 11, 13, 14, 17)
- R)-2′
-
6. A (2′
- R)-2′
-deoxy-2′
-fluoro-2′
-C-methyl nucleoside (β
-D) or its pharmaceutically acceptable salt thereof of the formula;
- View Dependent Claims (12, 18)
- R)-2′
-
15. A (2′
- R)-2′
-deoxy-2′
-fluoro-2′
-C-methyl nucleoside (β
-D) or its pharmaceutically acceptable salt thereof of the formula;
- View Dependent Claims (16, 19)
- R)-2′
Specification