Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion
First Claim
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1. A method of treating diabetes in a patient so afflicted, comprising:
- implanting one or more system control units in the patient, wherein one or more of the system control units are connected to and control one or more electrodes and/or drug delivery catheters that are implanted in the brain of the patient; and
delivering a stimulus configured to treat diabetes with one or more of the system control units via the one or more electrodes and/or drug delivery catheters to at least one of a ventromedial prefrontal cortex and a dorsolateral prefrontal cortex.
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Abstract
Systems and methods for introducing one or more stimulating drugs and/or applying electrical stimulation to the brain to at least treat or prevent diabetes uses at least one system control unit (SCU) producing electrical pulses delivered via electrodes implanted in the brain and/or producing drug infusion pulses, wherein the stimulating drug(s) are delivered to targeted areas in the brain.
199 Citations
19 Claims
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1. A method of treating diabetes in a patient so afflicted, comprising:
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implanting one or more system control units in the patient, wherein one or more of the system control units are connected to and control one or more electrodes and/or drug delivery catheters that are implanted in the brain of the patient; and delivering a stimulus configured to treat diabetes with one or more of the system control units via the one or more electrodes and/or drug delivery catheters to at least one of a ventromedial prefrontal cortex and a dorsolateral prefrontal cortex. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method of treating diabetes in a patient so afflicted, comprising:
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implanting one or more system control units in the patient, wherein one or more of the system control units are connected to and control one or more electrodes and/or drug delivery catheters that are implanted in the brain of the patient; and delivering a stimulus configured to treat diabetes with one or more of the system control units via the one or more electrodes and/or drug delivery catheters to at least an area of a right orbitofrontal cortex, an anterior insula, a dorsal putamen, and a basolateral amygdala (BLA). - View Dependent Claims (11, 12)
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13. A method of treating diabetes in a patient so afflicted, comprising:
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implanting one or more system control units in the patient, wherein one or more of the system control units are connected to and control one or more electrodes and/or drug delivery catheters that are implanted in the brain of the patient; and delivering a stimulus configured to treat diabetes with one or more of the system control units via the one or more electrodes and/or drug delivery catheters to at least one of a ventral tegmental area (VTA), a nucleus accumbens (NA), a hippocampus, a caudate nucleus, and a superior temporal. - View Dependent Claims (14, 15)
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16. A method of modulating the basal metabolic rate in a diabetic patient, comprising:
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implanting one or more system control units in the patient, wherein one or more of the system control units are connected to and control one or more electrodes and/or drug delivery catheters that are implanted in the brain of the patient; and delivering a stimulus configured to modulate basal metabolic rate to at least one or more of a hypothalamus, a thyroid, a pituitary, and a locus coeruleus. - View Dependent Claims (17, 18, 19)
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Specification