Process for the preparation of cinacalcet base

  • US 7,449,603 B2
  • Filed: 04/27/2007
  • Issued: 11/11/2008
  • Est. Priority Date: 04/27/2006
  • Status: Expired due to Fees
First Claim
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1. A process for preparing cinacalcet, comprising:

  • a) reducing 3-trifluoromethyl cinnamic acid to obtain 3-[3-(trifluoromethyl) phenyl]propanoic acid;

    b) optionally, converting the 3-[3-(trifluoromethyl)phenyl]propanoic acid into a compound of formula III

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