Methods of treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
DCFirst Claim
1. A method of treating irritable bowel syndrome in a subject, comprising:
- providing a composition comprising rifaximin; and
administering the composition to the subject in an amount sufficient to at least partially eradicate small intestinal bacterial overgrowth in the subject, whereby the irritable bowel syndrome is treated.
1 Assignment
Litigations
0 Petitions
Accused Products
Abstract
Disclosed is a method of diagnosing irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, such as multiple sclerosis and systemic lupus erythematosus, or Crohn'"'"'s disease, which involves detecting the presence of small intestinal bacterial overgrowth (SIBO) in a human subject having at least one symptom associated with a suspected diagnosis of any of those diagnostic categories. Also disclosed is a method of treating these disorders, and other disorders caused by SIBO, that involves at least partially eradicating a SIBO condition in the human subject. The method includes administration of anti-microbial or probiotic agents, or normalizing intestinal motility by employing a prokinetic agent. The method improves symptoms, including hyperalgesia related to SIBO and disorders caused by SIBO. Also disclosed is a kit for the diagnosis or treatment of irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, attention deficit/hyperactivity disorder, autoimmune diseases, or Crohn'"'"'s disease.
-
Citations
21 Claims
-
1. A method of treating irritable bowel syndrome in a subject, comprising:
-
providing a composition comprising rifaximin; and administering the composition to the subject in an amount sufficient to at least partially eradicate small intestinal bacterial overgrowth in the subject, whereby the irritable bowel syndrome is treated. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
-
12. A method of treating irritable bowel syndrome in a human subject, comprising:
-
providing a composition comprising rifaximin; and administering the composition to the human subject, wherein the administering relieves symptoms of irritable bowel syndrome. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21)
-
Specification