Compositions and methods for treating mammals with modified alginates and modified pectins

• US 7,452,871 B2
• Filed: 11/28/2005
• Issued: 11/18/2008
• Est. Priority Date: 02/23/1999
• Status: Expired due to Fees

• Current Assignee: Econugenics Incorporated
• Original Assignee: Econugenics Incorporated
• Inventors: Eliaz, Isaac
• Primary Examiner(s): Fay; Zohreh A
• Application Number:
  US11/287,208
• Publication Number:
  US 20060074052A1
• Time in Patent Office: 1,086 Days
• Field of Search: None
• US Class Current: 514/54
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/729 Agar; Agarose; Agaropectin
• CPC Class Codes: A61K 31/732 Pectin
• CPC Class Codes: A61K 31/734 Alginic acid
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Abstract

A modified alginate and/or modified pectin composition and method for preventing and/or treating diseases and/or conditions caused by circulating agents such as poisonous heavy metals, environmental toxins, calcium and cholesterol, is provided. The composition includes a modified alginate having a molecular weight of no more than 40,000 daltons and/or a modified pectin having a molecular weight of no more than 40,000 daltons. The method involves orally or intravenously administering the modified alginate and/or modified pectin composition, alone or with excipient.

Claims

1. A method of treating a condition or disease mediated by an agent selected from the group consisting of a poisonous metal, an environmental toxin and calcium circulating in the blood, the disease or condition being selected from the group consisting of blood poisoning, calcinosis, and dermatomyositis, the method comprising administering to a mammal in need of same an effective amount of pectin comprised of partially esterified polymers of galacturonic acid having a molecular weight of no more than 40,000 daltons, in an amount to effectively bind said agent.

2. The method of claim 1, wherein said condition is metal poisoning, and said agent is a poisonous heavy metal.

3. The method of claim 2, wherein said heavy metal is selected from the group consisting of aluminum, antimony, beryllium, bismuth, mercury, platinum, thallium, thorium, tin, tungsten, uranium, lead, cadmium, arsenic, silver, nickel, radioactive metals and mixtures thereof.

4. The method of claim 1, wherein said pectin is administered orally or intravenously.