Long term ambulatory intra-aortic balloon pump

• US 7,468,050 B1
• Filed: 12/24/2003
• Issued: 12/23/2008
• Est. Priority Date: 12/27/2002
• Status: Active Grant

• Current Assignee: L3 Technologies, Inc. (L3Harris Technologies, Inc.)
• Original Assignee: L3 Technologies, Inc. (L3Harris Technologies, Inc.)
• Inventors: Kantrowitz, Allen B.
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US10/746,543
• Time in Patent Office: 1,826 Days
• Field of Search: 604/18, 604 9601- 9903, 600 16- 18
• US Class Current: 604/96.01
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: A61M 60/139 inside the aorta, e.g. intra-aortic balloon pumps
• CPC Class Codes: A61M 60/274 the inlet and outlet being the same, e.g. para-aortic counter-pulsation blood pumps
• CPC Class Codes: A61M 60/295 Balloon pumps for circulatory assistance
• CPC Class Codes: A61M 60/497 for balloon pumps for circulatory assistance
• CPC Class Codes: A61M 60/88 Percutaneous cables

Abstract

A long term intra-aortic balloon pump (LTIABP) includes an enlarged pumping chamber on the order of 50 cc to 65 cc, inclusive. The pumping chamber is an intra luminal, large volume, long term balloon pump. The balloon pump can include tapered longitudinal ends and/or be segmented into a plurality of pumping chamber segments, each pumping chamber subsegment separated by a flexible power conduit link, where the diameter of the pumping chamber subsegments are independent of one another such as decreasing in size as the subsegments are further from the heart to accommodate the decreasing diameter of the aorta. The LTIABP can be used with any skin connector, or can be used with a percutaneous access device (PAD). The PAD can be sized and shaped to be surgically implanted in any desired location of the patient corresponding to the particular entry selected for implantation of a temporary IABP or LTIABP.

Claims

1. A long-term ambulatory intra-aortic balloon pump system for providing left ventricular cardiac assistance to a patient comprising:

an external drive system for supplying a compressed fluid, the drive system operating in accordance with a control program stored in memory; and

an intra-luminal balloon pump having at least two elongate inflatable chambers, the intra-luminal balloon pump positionable to be lying completely within a descending aorta of the patient, the at least two elongate inflatable chambers connectible in fluid communication for simultaneously inflating and deflating the at least two elongate chambers synchronously with a heartbeat of the patient in accordance with the control program stored in memory of the external drive system,

wherein the at least two elongate inflatable chambers are configured in series along a conduit with adjacent elongate inflatable chambers longitudinally interposed with a flexible conduit link, the configuration allowing individual chambers to align relationship with along a local longitudinal axis of a corresponding local segment of surrounding aortic lumen in a non-planar, non-uniform radius of curvature relationship, and

wherein the elongate inflatable chambers are individually sized such that an inflated chamber does not increase a cross-section of the local segment of surrounding aorta.

2. The system of claim 1 further comprising:

a percutaneous access device implantable with respect to a patient for connecting in fluid communication with the compressed fluid to be supplied by the external drive system.

3. The system of claim 2, wherein the external drive system supplies compressed air to the percutaneous access device through a large diameter conduit.

4. The system of claim 1, wherein the at least two elongate inflatable chambers further comprises at least three elongate inflatable chambers longitudinally separated from one another in series by flexible conduit links allowing individual chambers to align along the local longitudinal axis of the corresponding a local segment of surrounding aortic lumen.

5. The system of claim 1, wherein the at least two elongate inflatable chambers further comprises at least four elongate inflatable chambers longitudinally separated from one another in series by flexible conduit links allowing individual chambers to align along the local longitudinal axis of the corresponding local segment of surrounding aortic lumen.

6. The system of claim 1 further comprising:

each of the at least two elongate inflatable chambers having an inwardly tapering sidewall adjacent at least one end.

7. The system of claim 1 further comprising:

each of the at least two elongate inflatable chambers having an inwardly tapering sidewall adjacent each longitudinal end.

8. The system of claim 1, wherein the at least two inflatable chambers has an inflated volume of between 50 cc to 65 cc, inclusive.

9. The system of claim 1, wherein the at least two inflatable chambers has an inflated volume of between 50 cc to 65 cc, inclusive.

10. The system of claim 1, wherein the at least two inflatable chambers further comprises a plurality of inflatable chambers increasing in size from a proximal location with respect to an end of an interconnecting conduit to a distal location with respect to the end of the interconnecting conduit for positioning in the descending aorta of the patient from a proximal insertion point with respect to the descending aorta.

11. The system of claim 1, wherein the at least two inflatable chambers further comprises a plurality of inflatable chambers decreasing in size from a proximal location with respect to an end of an interconnecting conduit to a distal location with respect to the end of the interconnecting conduit for positioning in the descending aorta of the patient from a distal insertion point with respect to the descending aortic tree and major branches.

12. The system of claim 1, wherein all of the at least two inflatable chambers of the elongate intra-luminal balloon pump are positionable to be lying located completely downstream of the aortic arch and it'"'"'s major branches to the arm, head, and neck.

13. In a long-term ambulatory intra-aortic balloon pump system for providing left ventricular cardiac assistance to a patient, the improvement comprising:

an intra-luminal balloon pump having a plurality of elongate inflatable chambers, the intra-luminal balloon pump positionable to be lying completely within a descending aorta of the patient and interconnected by a common fluid supply line for simultaneously inflating and deflating the plurality of elongate chambers synchronously with respect to a heartbeat of the patient,

wherein adjacent elongate chambers are interposed with a flexible conduit link and separately and individually alignable with discrete local segments of surrounding aortic lumen in a non-linear relationship with respect to one another, and

wherein the plurality of elongate inflatable chambers are individually sized such that an inflated chamber does not increase a cross-section of the associated segment of surrounding aorta lumen.

14. The system of claim 13, wherein the plurality of elongate chambers define a non-uniform radius of curvature with respect to one another.

15. The system of claim 13, wherein the plurality of inflatable chambers vary in size from a proximal location with respect to an end of an interconnecting conduit to a distal location with respect to the end of the interconnecting conduit for positioning in the descending aorta of the patient from one of a proximal insertion point with respect to the descending aorta, and a distal insertion point with respect to the descending aortic tree and major branches.

16. The system of claim 13 further comprising:

a large diameter fluid power conduit connected with the plurality of inflatable chambers for communicating fluid to inflate and deflate the plurality of chambers simultaneously.

17. The system of claim 13, wherein the plurality of inflatable chambers have a total inflated volume of between 60 cc to 65 cc, inclusive.

18. A long-term ambulatory intra-aortic balloon pump system for providing left ventricular cardiac assistance to a patient comprising:

an external drive system for supplying a compressed fluid, the drive system operating in accordance with a control program stored in memory;

a percutaneous access device implantable with respect to a patient for connecting in fluid communication with the compressed fluid to be supplied by the external drive system, the percutaneous access device having an enlarged implantable flange portion with a reduced dimension neck portion extending outwardly to a location external of the patient for supporting a fitting for releasably connecting the compressed fluid supplied by the external drive system; and

an intra-luminal balloon pump having at least two elongate inflatable chambers, the intra-luminal balloon pump positionable to be lying completely within a descending aorta of the patient, the at least two elongate inflatable chambers connectible in fluid communication with the percutaneous access device for simultaneously inflating and deflating each chamber synchronously with a heartbeat of the patient in accordance with the control program stored in memory of the external drive system,

wherein the at least two elongate inflatable chambers are configured in series along a conduit with adjacent chambers longitudinally interposed with a flexible conduit link, the configuration allowing individual chambers to align along a local longitudinal axis of a corresponding local segment of surrounding aortic lumen in a non-planar, non-uniform radius of curvature relationship with respect to one another, and

wherein the elongate inflatable chambers are individually sized such that an inflated chamber does not increase a cross-section of the associated segment of surrounding aorta lumen.

19. The system of claim 18 further comprising:

each of the plurality of elongate inflatable chambers having an inwardly tapering sidewall adjacent at least one end.

20. The system of claim 18 further comprising:

each of the plurality of elongate inflatable chambers having an inwardly tapering sidewall adjacent each longitudinal end.

21. The system of claim 18, wherein the external drive system supplies compressed air to the percutaneous access device through a large diameter conduit.

22. The system of claim 18, wherein the plurality of inflatable chambers increase in size from a proximal location with respect to an end of an interconnecting conduit to a distal location with respect to the end of the interconnecting conduit for positioning in the descending aorta of the patient from a proximal insertion point with respect to the descending aorta.

23. The system of claim 18, wherein the plurality of inflatable chambers decrease in size from a proximal location with respect to an end of an interconnecting conduit to a distal location with respect to the end of the interconnecting conduit for positioning in the descending aorta of the patient from a distal insertion point with respect to the descending aortic tree and major branches.

24. The system of claim 18, wherein all of the plurality of inflatable chambers of the elongate intra-luminal balloon pump are positionable to be lying located completely downstream of the aortic arch and carotid arteries.