Treatment or pre-treatment for radiation/chemical exposure
First Claim
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1. The method of treatment for a tissue, organ or entire body of a patient after exposure to chemicals, radiation or both comprises the steps of:
- treating a patient after exposure to chemicals, radiation or both;
activating an acoustic shock wave or pressure pulse generator or source to emit pressure pulses or acoustic shock waves directed toward the tissue to impinge the tissue with shock waves having a low energy density in the range of 0.000001mJ/mm2 to 1.0mJ/mm2, the pressure pulse being an acoustic pulse which includes several cycles of positive and negative pressure, wherein the pressure pulse has an amplitude of the positive part of such a cycle should be above 0.1 MPa and the time duration of the pressure pulse is from below a microsecond to about a second, rise times of the positive part of the first pressure cycle in the range of nano-seconds (ns) up to some milli-seconds (ms), the acoustic shock waves being very fast pressure pulses having amplitudes above 0.1 MPa and rise times of the amplitude being below 100'"'"'s of ns, the duration of the shock wave is typically below 1-3 micro-seconds (μ
s) for the positive part of a cycle and typically above some micro-seconds for the negative part of a cycle; and
subjecting the tissue, organ or entire body to convergent, divergent, planar or near planar acoustic shock waves or pressure pulses treatment energy density and treatment dosage stimulating said tissue, organ or body wherein the tissue, organ or body is positioned within a path of the emitted shock waves and away from any localized geometric focal volume or point of the emitted shock waves wherein the emitted shock waves or pressure pulses either have no geometric focal volume or point or have a focal volume or point ahead of the tissue or beyond the tissue thereby passing the emitted waves or pulses through the tissue while avoiding having any localized focal point within the tissue and wherein the emitted pressure pulses or shock waves are convergent, divergent, planar or near planar and the pressure pulse shock wave generator or source is based on electro-hydraulic, electromagnetic, piezoceramic or ballistic wave generation having an energy density value ranging as low as 0.00001 mJ/mm2 to a high end of below 1.0 mJ/mm2.
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Abstract
A method of treatment for a tissue organ or entire body of a patient prior to or after exposure to chemicals or radiation or both comprises the steps of activating an acoustic shock wave generator or source to emit acoustic shock waves; and subjecting the tissue, organ or entire body to the acoustic shock waves stimulating said tissue, organ or body wherein the tissue, organ or body is positioned within a path of the emitted shock waves.
29 Citations
14 Claims
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1. The method of treatment for a tissue, organ or entire body of a patient after exposure to chemicals, radiation or both comprises the steps of:
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treating a patient after exposure to chemicals, radiation or both; activating an acoustic shock wave or pressure pulse generator or source to emit pressure pulses or acoustic shock waves directed toward the tissue to impinge the tissue with shock waves having a low energy density in the range of 0.000001mJ/mm2 to 1.0mJ/mm2, the pressure pulse being an acoustic pulse which includes several cycles of positive and negative pressure, wherein the pressure pulse has an amplitude of the positive part of such a cycle should be above 0.1 MPa and the time duration of the pressure pulse is from below a microsecond to about a second, rise times of the positive part of the first pressure cycle in the range of nano-seconds (ns) up to some milli-seconds (ms), the acoustic shock waves being very fast pressure pulses having amplitudes above 0.1 MPa and rise times of the amplitude being below 100'"'"'s of ns, the duration of the shock wave is typically below 1-3 micro-seconds (μ
s) for the positive part of a cycle and typically above some micro-seconds for the negative part of a cycle; andsubjecting the tissue, organ or entire body to convergent, divergent, planar or near planar acoustic shock waves or pressure pulses treatment energy density and treatment dosage stimulating said tissue, organ or body wherein the tissue, organ or body is positioned within a path of the emitted shock waves and away from any localized geometric focal volume or point of the emitted shock waves wherein the emitted shock waves or pressure pulses either have no geometric focal volume or point or have a focal volume or point ahead of the tissue or beyond the tissue thereby passing the emitted waves or pulses through the tissue while avoiding having any localized focal point within the tissue and wherein the emitted pressure pulses or shock waves are convergent, divergent, planar or near planar and the pressure pulse shock wave generator or source is based on electro-hydraulic, electromagnetic, piezoceramic or ballistic wave generation having an energy density value ranging as low as 0.00001 mJ/mm2 to a high end of below 1.0 mJ/mm2. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. The method of treatment for a tissue, organ or entire body of a patient prior to exposure to chemicals, radiation or both comprises the steps of:
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receiving the patient pre-occurrence to being exposed to chemicals, radiation or both; activating an acoustic shock wave or pressure pulse generator or source to emit acoustic shock waves or pressure pulses directed toward the tissue to impinge the tissue with shock waves or pressure pulses having a low energy density in the range of 0.000001 mJ/mm2 to 1.0 mJ/mm2, the pressure pulse being an acoustic pulse which includes several cycles of positive and negative pressure, wherein the pressure pulse has an amplitude of the positive part of such a cycle should be above 0.1 MPa and the time duration of the pressure pulse is from below a microsecond to about a second, rise times of the positive part of the first pressure cycle in the range of nano-seconds (ns) up to some milli-seconds (ms),the acoustic shock waves being very fast pressure pulses having amplitudes above 0.1 MPa and rise times of the amplitude being below 100'"'"'s of ns, the duration of the shock wave is typically below 1-3 micro-seconds (μ
s) for the positive part of a cycle and typically above some micro-seconds for the negative part of a cycle; andsubjecting the tissue, organ or entire body to convergent, divergent, planar or near planar acoustic shock waves or pressure pulses treatment energy density and treatment dosage stimulating said tissue, organ or body in the absence of creating cavitation bubbles in the treated tissue, organ or body wherein the treated tissue, organ or body is positioned within a path of the emitted shock waves or pressure pulses and away from any localized geometric focal volume or point of the emitted shock waves or pressure pulses wherein the emitted shock waves or pressure pulses either have no geometric focal volume or point or have a focal volume or point ahead of the tissue or beyond the tissue thereby passing the emitted waves or pulses through the tissue while avoiding having any localized focal point within the tissue wherein the emitted pressure pulses or shock waves are convergent, divergent, planar or near planar and the pressure pulse shock wave generator or source is based on electro-hydraulic, electromagnetic, piezoceramic or ballistic wave generation having an energy density value ranging as low as 0.00001 mJ/mm2 to a high end of below 1.0 mJ/mm2;
both the treatment energy density and treatment dosage are selected to avoid cell damage as evidenced by the avoidance of cell hemorrhaging within the tissue caused by cavitation. - View Dependent Claims (10, 11, 12, 13, 14)
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Specification
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Current AssigneeSoftwave Tissue Regeneration Technologies, LLC
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Original AssigneeGeneral Patent, LLC (Tissue Regeneration Technologies LLC)
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InventorsSchaden, Wolfgang, Warlick, John, Schultheiss, Reiner
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Primary Examiner(s)Casler; Brian
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Assistant Examiner(s)RAMIREZ, JOHN FERNANDO
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Application NumberUS11/238,524Publication NumberTime in Patent Office1,335 DaysField of Search601 2- 4, 600437-461, 600/427US Class Current601/2CPC Class CodesA61B 17/22004 using mechanical vibrations...A61N 7/00 Ultrasound therapy lithotri...
