Sensor

• US 7,550,290 B2
• Filed: 05/11/2004
• Issued: 06/23/2009
• Est. Priority Date: 05/15/2003
• Status: Expired due to Fees

• Current Assignee: Panasonic Healthcare Holdings Co., Ltd.
• Original Assignee: Panasonic Corporation (Panasonic Holdings Corporation)
• Inventors: Yamamoto, Tomohiro
• Primary Examiner(s): Soohoo; Tony G
• Assistant Examiner(s): Eom; Robert
• Application Number:
  US10/548,200
• Publication Number:
  US 20060099107A1
• Time in Patent Office: 1,869 Days
• Field of Search: 204/403.4, 204/193, 204/403.06, 204/400, 205/777.5
• US Class Current: 435/287.8
• CPC Class Codes: B01L 2200/0684 Venting, avoiding backpressure, avoid gas bubbles
• CPC Class Codes: B01L 2300/0663 Whole sensors
• CPC Class Codes: B01L 2300/0681 Filter
• CPC Class Codes: B01L 2300/0825 Test strips
• CPC Class Codes: B01L 2300/0874 Three dimensional network
• CPC Class Codes: B01L 2300/0887 Laminated structure
• CPC Class Codes: B01L 2400/0406 capillary forces
• CPC Class Codes: B01L 3/50273 characterised by the means or forces applied to move the fluids micropumps F04B19/006, of the membrane type F04B43/043
• CPC Class Codes: B01L 3/502753 characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation separation in general B01D; microapparatus for analysis using electrophoresis G01N27/44791; sample preparation G01N1/28
• CPC Class Codes: C12Q 1/002 Electrode membranes
• CPC Class Codes: G01N 33/48707 by electrical means G01N33/49, G01N33/493 take precedence
• CPC Class Codes: Y10S 435/817 Enzyme or microbe electrode
• CPC Class Codes: Y10S 436/806 Electrical property or magnetic property

Abstract

In order to realize a sensor that is capable of promptly and accurately supplying a small amount of a liquid sample to a filtration part even if the sensor is not held substantially horizontally, this invention provides a sensor having means for supplying a liquid sample to the filtration part by capillary action.

Claims

1. A sensor comprising:

a reaction part, a filtration part, and a supply means,

wherein,

said reaction part, said filtration part, and said supply means are stacked in this order,

said supply means being provided for supplying a liquid sample to said filtration part by capillary action,

said filtration part including a filter for supplying a filtered liquid sample to said reaction part,

said reaction part having a reagent that reacts with said liquid sample that has been filtered in said filter,

said reaction part including a base plate and a plate-like reaction part spacer that are stacked in order,

said plate-like reaction part spacer having a cavity inside, said cavity provided with said reagent,

said supply means including a plate-like bottom cover, plate-like spacers, and a plate-like top cover that are stacked in order, said plate-like spacers providing a space inside,

said plate-like spacers providing at the side faces thereof a first opening and an air vent, each facing to the direction parallel to the surface of said base plate;

said plate-like bottom cover having a second opening,

said space and said second opening being communicated,

the width of said space narrows in the direction from said first opening toward said second opening, seen in planar view, or, the width of said space from said first opening until said second opening is fixed, seen in planar view, so that said liquid sample that is injected from said first opening is directed toward said second opening by capillary action.

2. The sensor in accordance with claim 1, wherein the width of said space narrows from said first opening toward said second opening, seen in planar view.

3. The sensor in accordance with claim 2, wherein the width of said space narrows from said air vent toward said second opening, seen in planar view.

4. The sensor in accordance with claim 1, wherein the width of said space from said first opening until said second opening is fixed, seen in planar view.

5. The sensor in accordance with claim 1, wherein the cross-sectional area of said second opening is smaller than the cross-sectional area of said filter.

6. The sensor in accordance with claim 5, wherein the cross-section of said second opening is similar to the cross-section of said filter.

7. The sensor in accordance with claim 6, wherein the volume of said space from said first opening to said second opening is equal to or larger than the total volume of the volume of a gap around said filter and the volume of a space inside said reaction part.

8. The sensor in accordance with claim 1, wherein said reaction part has a second air vent.