Single-use external dosimeters for use in radiation therapies
First Claim
Patent Images
1. A method for monitoring radiation doses administered to patients undergoing radiation treatments, comprising the steps of:
- releasably securing at least one single-use dosimeter sensor patch comprising an electronic memory held thereon, the patch secured to be in intimate contact with the skin of the patient such that during operation, the patch is self-contained and devoid of wires extending therefrom;
administering radiation to the patient in a first treatment session after the securing step;
contacting the self-contained sensor patch with a dose-reader device after the administering step to obtain data associated with a change in an operational parameter in the dosimeter sensor patch and to obtain data from the electronic memory; and
determining the radiation dose received by the patient during the administering step based on the change in the operational parameter.
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Abstract
Methods, systems, devices, and computer program products include positioning disposable single-use radiation sensor patches that have adhesive means onto the skin of a patient to evaluate the radiation dose delivered during a treatment session. The sensor patches are configured to be minimally obtrusive and operate without the use of externally extending power chords or lead wires.
205 Citations
92 Claims
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1. A method for monitoring radiation doses administered to patients undergoing radiation treatments, comprising the steps of:
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releasably securing at least one single-use dosimeter sensor patch comprising an electronic memory held thereon, the patch secured to be in intimate contact with the skin of the patient such that during operation, the patch is self-contained and devoid of wires extending therefrom; administering radiation to the patient in a first treatment session after the securing step; contacting the self-contained sensor patch with a dose-reader device after the administering step to obtain data associated with a change in an operational parameter in the dosimeter sensor patch and to obtain data from the electronic memory; and determining the radiation dose received by the patient during the administering step based on the change in the operational parameter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A method for monitoring radiation doses administered to patients undergoing radiation treatments, comprising the steps of:
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releasably securing at least one single-use dosimeter sensor patch onto the skin of the patient such that the patch is self-contained and devoid of wires extending therefrom; providing an overlay material over the surface of the sensor patch to simulate a subsurface placement of the sensor patch corresponding to a desired distance beneath the skin of the patient; administering radiation to the patient in a first treatment session; contacting the sensor patch with a dose-reader device after the administering step to obtain data associated with a change in an operational parameter in the dosimeter sensor patch; and determining the radiation dose received by the patient during the administering step based on the change in the operational parameter - View Dependent Claims (32, 33, 34, 35)
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36. A system for monitoring radiation administered to a patient during a therapeutic treatment, the system comprises:
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at least one single-use self-contained dosimeter patch, the patch comprising a body configured to be in intimate contact with skin of a patient, the patch holding a circuit with at least one MOSFET and an external reader contact region thereon, the at least one MOSFET having an associated threshold voltage that changes when exposed to radiation, the body comprising opposing upper and lower primary surfaces; and an external portable dose-reader being configured to make electrical contact with the patch by physically engaging with the contact region on the patch to obtain voltage threshold data corresponding to the dose amount of radiation exposure it is exposed to in use, wherein the patch has a perimeter that is devoid of outwardly extending loose lead wires. - View Dependent Claims (37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58)
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59. A system for monitoring radiation administered to a patient during a therapeutic treatment, the system comprises:
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at least one single-use dosimeter patch, the patch comprising a body holding a circuit with at least one MOSFET and an external reader contact region thereon, the at least one MOSFET having an associated threshold voltage that changes when exposed to radiation, the body comprising opposing upper and lower primary surfaces; and an external portable dose-reader being configured to make electrical contact with the patch by physically engaging with the contact region on the patch to obtain voltage threshold data corresponding to the dose amount of radiation exposure it is exposed to in use, wherein the patch has a perimeter that is devoid of outwardly extending loose lead wires, and wherein the at least one MOSFET includes a MOSFET pair, wherein the MOSFET pair are differentially biased during irradiation to create different voltage offsets.
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60. A system for monitoring radiation administered to a patient during a therapeutic treatment, the system comprises:
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at least one single-use dosimeter patch, the patch comprising a body holding a circuit with at least one MOSFET and an external reader contact region thereon, the at least one MOSFET having an associated threshold voltage that changes when exposed to radiation, the body comprising opposing upper and lower primary surfaces; and an external portable dose-reader being configured to make electrical contact with the patch by physically engaging with the contact region on the patch to obtain voltage threshold data corresponding to the dose amount of radiation exposure it is exposed to in use, wherein the patch has a perimeter that is devoid of outwardly extending loose lead wires, and wherein the at least one MOSFET includes a MOSFET pair, wherein one of the MOSFETs in the pair is selectively implanted with dopant ions to shift the threshold voltage with respect to the other MOSFET and/or to increase the radiation sensitivity of the implanted MOSFET relative to the other MOSFET.
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61. A system for monitoring radiation administered to a patient during a therapeutic treatment, the system comprises:
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at least one single-use dosimeter patch, the patch comprising a body holding a circuit with at least one MOSFET and an external reader contact region thereon, the at least one MOSFET having an associated threshold voltage that changes when exposed to radiation, the body comprising opposing upper and lower primary surfaces; an overlay material over the surface of the at least one sensor patch to simulate a subsurface placement of the at least one sensor patch corresponding to a desired distance beneath the skin of the patient; and an external portable dose-reader being configured to make electrical contact with the patch by physically engaging with the contact region on the patch to obtain voltage threshold data corresponding to the dose amount of radiation exposure it is exposed to in use, wherein the patch has a perimeter that is devoid of outwardly extending loose lead wires. - View Dependent Claims (62, 63, 64, 65)
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- 66. An oncology single-use external use radiation dosimeter patch, the patch comprising a substantially conformable resilient substrate holding a circuit comprising at least one FET that changes a parameter in a detectable predictable manner when exposed to radiation, and wherein the patch comprises electronic memory that is configured to communicate with an external reader that electronically determines a radiation dose amount based on data from the patch and stores the radiation dose amount in the electronic memory, the body comprising opposing upper and lower primary surfaces, wherein the dosimeter patch, in use and position on a patient, is devoid of externally extending lead wires, and wherein the patch is a single-use self-contained dosimeter patch that is adhesively secured to skin of an oncology patient.
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77. An oncologic external single-use radiation dosimeter patch, the patch comprising a substantially conformable resilient substrate holding a circuit with an operational electronic component that changes a parameter in a detectable predictable manner when exposed to radiation, the body comprising opposing upper and lower primary surfaces, wherein the dosimeter patch, in use, is devoid of externally extending lead wires and wherein the patch is a single-use dosimeter patch that is adhesively secured to the skin of a patient,
wherein the at least one MOSFET is a pair of MOSFETs, wherein one of the MOSFETs in the pair is selectively implanted with dopant ions so as to shift its threshold voltage relative to that of the other MOSFET and/or to increase the sensitivity of the implanted MOSEET relative to the other MOSFET to thereby allow a differential voltage measurement to be obtained to measure radiation.
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78. An oncology medical set-of single-use radiation dosimeter patches comprising:
a plurality of discrete single-use self-contained dosimeter patches, each patch comprising a substantially conformable resilient substrate holding a circuit with an operational electronic component that changes a parameter in a detectable predictable manner when exposed to radiation, wherein the patches comprise an electronic memory that engages an external reader to provide calibration data associated with the circuit components and that accepts and stores a calculated radiation dose associated with the patch, the body comprising opposing upper and lower primary surfaces, and wherein the dosimeter patch, in use, is devoid of externally hanging lead wires, and wherein the patches are configured to detect radiation doses in the range of at least from about 10 to about 200 cGy. - View Dependent Claims (79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92)
Specification