SPG stimulation via the greater palatine canal
First Claim
Patent Images
1. Apparatus for application to a subject, comprising:
- an elongated support element having a length of between 1.8 cm and 4 cm, and having proximal and distal ends;
one or more electrodes fixed to the support element in a vicinity of the distal end thereof, and adapted to apply an electrical current to a sphenopalatine ganglion (SPG) of the subject;
a receiver, fixed to the support element, and electrically coupled to the electrodes;
a wireless transmitter, adapted to be placed in an oral cavity of the subject, and to be wirelessly coupled to the receiver; and
an oral appliance, adapted to be fixed to the transmitter, and shaped so as to define a surface that fits closely to a roof of the oral cavity.
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Accused Products
Abstract
Apparatus for application to a subject is provided, including an elongated support element having a length of between 1.8 cm and 4 cm, and having proximal and distal ends; and one or more electrodes fixed to the support element in a vicinity of the distal end thereof, and adapted to apply an electrical current to a sphenopalatine ganglion (SPG) of the subject. The apparatus further includes a receiver, fixed to the support element, and electrically coupled to the electrodes; and a wireless transmitter, adapted to be placed in an oral cavity of the subject, and to be wirelessly coupled to the receiver. Other embodiments are also described.
225 Citations
57 Claims
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1. Apparatus for application to a subject, comprising:
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an elongated support element having a length of between 1.8 cm and 4 cm, and having proximal and distal ends; one or more electrodes fixed to the support element in a vicinity of the distal end thereof, and adapted to apply an electrical current to a sphenopalatine ganglion (SPG) of the subject; a receiver, fixed to the support element, and electrically coupled to the electrodes; a wireless transmitter, adapted to be placed in an oral cavity of the subject, and to be wirelessly coupled to the receiver; and an oral appliance, adapted to be fixed to the transmitter, and shaped so as to define a surface that fits closely to a roof of the oral cavity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. Apparatus for application to a subject, comprising:
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an elongated support element having a length of between 1.8 cm and 4 cm, and having proximal and distal ends; one or more electrodes fixed to the support element in a vicinity of the distal end thereof, and adapted to apply an electrical current to a sphenopalatine ganglion (SPG) of the subject; a receiver, fixed to the support element, and electrically coupled to the electrodes; a wireless transmitter, adapted to be placed in an oral cavity of the subject, and to be wirelessly coupled to the receiver; and an oral appliance, which comprises; a capsule, which is configured to be placed and held between an alveolar process and an inner surface of a cheek of the subject; the transmitter; and an elongated coupling element, which couples the transmitter to the capsule.
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19. Apparatus for application to a subject, comprising:
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an elongated support element having a length of between 1.8 cm and 4 cm, and having proximal and distal ends; one or more electrodes fixed to the support element in a vicinity of the distal end thereof, and adapted to apply an electrical current to a sphenopalatine ganglion (SPG) of the subject; a receiver, fixed to the support element, and electrically coupled to the electrodes; a wireless transmitter, adapted to be placed in an oral cavity of the subject, and to be wirelessly coupled to the receiver; and an oral appliance, adapted to be fixed to the transmitter, and adapted to be coupled to a structure selected from the group consisting of;
a tooth of the subject, and gingival covering an alveolar process of the subject. - View Dependent Claims (20, 21, 22)
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23. Apparatus for application to a subject, comprising:
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an elongated support element having a length of between 1.8 cm and 4 cm, and having proximal and distal ends; one or more electrodes fixed to the support element in a vicinity of the distal end thereof, and adapted to apply an electrical current to a sphenopalatine ganglion (SPG) of the subject; a receiver, fixed to the support element, and electrically coupled to the electrodes; and a wireless transmitter, adapted to be placed in an oral cavity of the subject, and to be wirelessly coupled to the receiver, wherein the distal end of the support element comprises a surgical punch.
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24. Apparatus for application to a subject, comprising:
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an elongated support element having a length of between 1.8 cm and 4 cm, and having proximal and distal ends; one or more electrodes fixed to the support element in a vicinity of the distal end thereof, and adapted to apply an electrical current to a sphenopalatine ganglion (SPG) of the subject; a receiver, fixed to the support element, and electrically coupled to the electrodes; and a wireless transmitter, adapted to be placed in an oral cavity of the subject, and to be wirelessly coupled to the receiver, wherein at least a portion of the support element is adapted to be placed in a greater palatine canal of the subject, and wherein the support element comprises a lock, adapted to hold the support element in place after insertion thereof into the greater palatine canal.
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25. Apparatus for application to a subject, comprising:
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one or more electrodes adapted to apply an electrical current to tissue of the subject selected from the group consisting of;
a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, and a lesser deep petrosal nerve;a receiver, electrically coupled to the one or more electrodes; a wireless transmitter, adapted to be placed in an oral cavity of the subject, and to be wirelessly coupled to the receiver; and an oral appliance, adapted to be fixed to the transmitter, and shaped so as to define a surface that fits closely to a roof of the oral cavity. - View Dependent Claims (26, 27, 28)
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29. Apparatus comprising an implantable neural stimulator, which comprises:
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an elongated support element having a length of between 2.6 cm and 3 cm, having a distal end, and adapted to be placed in a greater palatine canal of a subject; one or more electrodes fixed to the support element in a vicinity of the distal end thereof, and adapted to apply an electrical current to a sphenopalatine ganglion (SPG) of the subject; and a needle shaped so as to define a sharp distal end and a bore, which bore is adapted to hold the support element and the electrodes during insertion of the support element and the electrodes into the greater palatine canal, and to be withdrawn from the greater palatine canal thereafter, leaving the support element and electrodes in the greater palatine canal, wherein the support element comprises a lock, adapted to hold the support element in place after insertion thereof into the greater palatine canal.
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30. A method comprising:
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placing an elongated support element, having a length of between 2.6 cm and 3 cm and having a distal end, into a bore of a needle shaped so as to define a sharp distal end; inserting, into a greater palatine canal of a subject, the needle holding the support element; withdrawing the needle from the greater palatine canal thereafter, leaving the support element in the greater palatine canal; and applying, from a vicinity of the distal end of the support element, an electrical current to a sphenopalatine ganglion (SPG) of the subject, wherein inserting the support element comprises locking the support element in place after insertion thereof into the greater palatine canal.
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31. A method comprising:
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wirelessly transmitting energy from within an oral cavity of a subject; receiving the energy; and using the received energy, applying an electrical current to tissue of the subject selected from the group consisting of;
a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, and a lesser deep petrosal nerve. - View Dependent Claims (32, 33, 34)
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35. A method comprising:
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inserting an elongated support element into a body of a subject, the element having a length of between about 1.8 cm and about 4 cm, and having proximal and distal ends; wirelessly transmitting energy from within an oral cavity of the subject; receiving the energy at the support element; and using the received energy, applying, from a vicinity of the distal end of the support element, an electrical current to a sphenopalatine ganglion (SPG) of the subject. - View Dependent Claims (36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57)
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Specification