Apparatus and methods for directional delivery of laser energy

• US 7,572,254 B2
• Filed: 09/16/2005
• Issued: 08/11/2009
• Est. Priority Date: 09/17/2004
• Status: Active Grant

• Current Assignee: Spectranetics Corporation (Koninklijke Philips N.V.)
• Original Assignee: Spectranetics Corporation (Koninklijke Philips N.V.)
• Inventors: Wood, Timothy J., Bowe, Wade A., Hebert, Chris J., Tedder, Scott
• Primary Examiner(s): Johnson, III; Henry M
• Assistant Examiner(s): CRANDALL, LYNSEY P
• Application Number:
  US11/228,845
• Publication Number:
  US 20060167442A1
• Time in Patent Office: 1,425 Days
• Field of Search: 606/7
• US Class Current: 606/15
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22061 for spreading elements apart
• CPC Class Codes: A61B 2018/2238 with means for selectively laterally deflecting the tip of the fibre

Abstract

In some embodiments, without limitation, the invention comprises a catheter having an elongated housing with a channel disposed therein. A laser delivery member is movable and at least partially disposed within the channel. A ramp is disposed within the housing at an angle to its central axis and proximate to its distal end. The ramp is adapted to move the distal end of the laser delivery member outwardly from the central axis of the housing. A guidewire biases the distal end of the laser delivery member generally inwardly toward the central axis of the housing. In some embodiments, without limitation, the offset of the central axis of the tip of the laser delivery member from the central axis of the housing is determined by adjusting the extent to which the laser delivery member travels on the ramp, and disposition of the laser delivery member on the guidewire maintains the offset tip substantially parallel to the central axis of the housing. Thus, in accordance with the invention, the distal end of the laser delivery member may be biased in a desired direction or offset, permitting ablation of an area larger than the area of the distal end of the catheter.

Claims

1. A catheter comprising:

an elongated housing having a central axis between a first proximal end and a first distal end, said housing having a channel disposed at least part way between said first proximal end and said first distal end, the elongated housing further including a tip at the first distal end, the tip having a first guidewire lumen;

a laser delivery member having a second proximal end and a second distal end and comprising at least one optical fiber, said laser member being at least partially disposed within said channel and movable therein, wherein the laser delivery member further includes a second guidewire lumen;

a cavity being disposed proximate said first distal end of said elongated housing and in communication with said channel;

a ramp proximate said first distal end of said elongated housing, said ramp being in communication with said channel and having an inclining proximal section and an apex section, said ramp adapted to move said second distal end of said laser delivery member laterally away from said central axis of said elongated member when the distal end of the laser delivery member is on the ramp; and

a guidewire extending through the second guidewire lumen of the laser delivery member, over the ramp and through the first guidewire lumen at the tip of the elongated housing, said guidewire being adapted to position said second distal end of said laser delivery member laterally away from and generally parallel to said central axis as the distal end of the laser delivery member is at or beyond the apex section of the ramp.

2. The catheter of claim 1, wherein said elongated housing is formed from a flexible material.

3. The catheter of claim 2, wherein said flexible material is sufficiently flexible to permit said housing to travel contralaterally within the vasculature of a mammal.

4. The catheter of claim 1, wherein said elongated housing includes a braided pattern along at least a portion of said housing.

5. The catheter of claim 1, wherein said elongated hosing includes a braided pattern along at least one half of a length of said housing.

6. The catheter of claim 1, wherein said elongated housing includes a round or flat metal ribbon wire embedded within said housing.

7. The catheter of claim 1, wherein said elongated housing includes a wire braid disposed proximate said first distal end.

8. The catheter of claim 1, wherein said elongated housing includes at least one wire disposed within said housing.

9. The catheter of claim 1, wherein said elongated housing includes a polymer tip disposed at said first distal end separate from or integrated into said housing.

10. The catheter of claim 1, wherein said elongated housing includes a stent-like structure disposed proximate at least one of said distal end, said proximal end, and therebetween.

11. The catheter of claim 10, wherein said stent-like structure is formed from one of stainless steel, cobalt-chromium, and nickel titanium or any combination thereof.

12. The catheter of claim 1, wherein said ramp is inflatable.

13. The catheter of claim 1, wherein said ramp is formed into an internal wall of said housing.

14. The catheter of claim 1, wherein said ramp is formed from one of a metal, plastic, and rubber.

15. The catheter of claim 1, wherein said ramp includes a marker band disposed along said ramp.

16. The catheter of claim 1, wherein said ramp includes at least one radiopaque marker disposed at a predetermined location along a longitudinal length of said ramp.

17. The catheter of claim 1, further comprising a support structure disposed at said first distal end of said housing.

18. The catheter of claim 17, wherein said support structure is integrated with said housing proximate said first distal end.

19. The catheter of claim 17, wherein said support structure includes an aperture in communication with said channel.

20. The catheter of claim 17, wherein said support structure includes a stent-like or coiled form.

21. The catheter of claim 17, wherein said support structure is progressively more flexible from a support structure proximal end to a support structure distal end.

22. The catheter of claim 17, wherein said support structure includes a surface comprising at least a portion having a stent-like pattern.

23. The catheter of claim 17, wherein said support structure includes said ramp molded into a surface of said support structure.

24. The catheter of claim 17, wherein said support structure supports said first distal end of said housing.

25. A catheter support structure comprising:

a housing having a proximal end, a distal end, a central axis, a proximal lumen, a distal lumen, and an aperture disposed at least partially within said housing so as to be between the proximal lumen and the distal lumen, wherein the proximal lumen and the distal lumen are adapted to hold a guidewire;

a ramp having an inclining proximal section and an apex section, said ramp being positioned between the proximal lumen and the distal lumen such that the apex is positioned laterally away from the proximal lumen and the distal lumen, the ramp being in communication with said aperture and adapted to move a distal end of a laser delivery member laterally away from said central axis after passing through the proximal lumen over the guidewire, and to position the distal end of the laser delivery member laterally away from and generally parallel to the central axis as the distal end of the laser delivery member is at or beyond the apex section of the ramp.

26. The catheter support structure of claim 25, wherein said ramp is molded into a surface of said housing.

27. The catheter support structure of claim 25, wherein said ramp is inflatable.

28. The catheter support structure of claim 25, wherein said ramp is formed into an internal wall of said housing.

29. The catheter support structure of claim 25, wherein said ramp is formed from one of a metal, plastic, and rubber, or any combination thereof.

30. The catheter support structure of claim 25, wherein said ramp includes a marker band disposed along said ramp.

31. The catheter support structure of claim 25, wherein said ramp includes at least one radiopaque marker disposed at a predetermined location along a longitudinal length of said ramp.

32. The catheter support structure of claim 25, wherein the distal lumen is adapted to receive a guidewire, said guidewire being adapted to bias the distal end of said laser delivery member generally inwardly toward said central axis.

33. The catheter support structure of claim 25, wherein said catheter support structure is integrated with a catheter housing.

34. The catheter support structure of claim 25, further comprising at least one flexible structure disposed proximate said distal end of said housing having a proximal end and a distal end, said at least one flexible structure is increasingly flexible from said proximal end to said distal end, and wherein said at least one flexible structure includes a stent-like or coiled form.

35. A catheter system, comprising:

a catheter sheath comprising a sheath body having a proximal end, a distal end, a proximal lumen, a distal lumen, a ramp disposed between the proximal lumen and the distal lumen, and an opening proximal to the ramp, wherein the ramp has an inclining proximal section and an apex section;

a laser delivery member having a proximal end and a distal end, wherein the laser delivery member is movable within the proximal lumen of the catheter sheath;

a guidewire adapted to extend through the proximal lumen and the distal lumen of the catheter sheath such that it passes over the ramp;

wherein the laser delivery member includes a guidewire lumen to permit the distal end of the laser delivery member to track along the guidewire as it moves along the ramp, with the guidewire adapted to position the distal end of the laser delivery member laterally away from and generally parallel to the central axis as the distal end of the laser delivery member is at or beyond the apex of the ramp.