Method and device for monitoring medication usage

CAFC
  • US 7,585,680 B2
  • Filed: 08/23/2004
  • Issued: 09/08/2009
  • Est. Priority Date: 08/28/2003
  • Status: Active Grant
First Claim
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1. A method for quantifying at least one metabolite in a biological sample comprising the steps of:

  • (a) providing one biological sample obtained from a patient on a prescribed medication regimen, wherein the sample comprises at least one test metabolite, wherein in the sample is urine;

    (b) providing one set of known normative data specific to a reference metabolite, wherein the set of data is collected from a population that is on a prescribed medication regimen;

    (c) contacting the biological sample with an analytical device;

    (d) detecting the presence of at least one test metabolite in the biological sample with the device, wherein the device is capable of measuring the concentration of the test metabolite in the sample;

    (e) normalizing the biological sample to adjust for changes in the patient'"'"'s hydration status by determining the metabolite/creatinine ratio of the patient; and

    (f) quantifying the concentration of at least one test metabolite in the biological sample by comparing a ratio between the concentration of the test metabolite from the patient to the set of known normative data specific to the reference metabolite concentration.

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