Locking mechanisms for fixation devices and methods of engaging tissue

• US 7,604,646 B2
• Filed: 05/16/2005
• Issued: 10/20/2009
• Est. Priority Date: 04/09/1999
• Status: Expired due to Term

• Current Assignee: Evalve, Inc. (Abbott Laboratories Incorporated)
• Original Assignee: Evalve, Inc. (Abbott Laboratories Incorporated)
• Inventors: Sarabia, Jaime E., Raschdorf, Alfred H., Goldfarb, Eric A., Madden, John P.
• Primary Examiner(s): Ho; (Jackie) Tan-Uyen T.
• Assistant Examiner(s): ANDERSON, GREGORY A
• Application Number:
  US11/130,818
• Publication Number:
  US 20060020275A1
• Time in Patent Office: 1,618 Days
• Field of Search: 606/213, 606/232, 623/2.12
• US Class Current: 606/151
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/08 Wound clamps or clips, i.e. not or only partly penetrating the tissue suture bridges A61B17/0466; Devices for bringing together the edges of a wound
• CPC Class Codes: A61B 17/10 for applying or removing wound clamps, e.g. containing only one clamp or staple A61B17/076 takes precedence; containing multiple wound clamps A61B17/068; Wound clamp magazines containers, packaging elements or packages specially adapted for particular articles or with special means for dispensing contents B65D83/00, B65D85/00
• CPC Class Codes: A61B 17/122 Clamps or clips , e.g. for the umbilical cord for the vas deferens A61F6/206
• CPC Class Codes: A61B 17/1285 for minimally invasive surgery
• CPC Class Codes: A61B 17/2909 Handles
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00783 Valvuloplasty
• CPC Class Codes: A61B 2017/2946 Locking means
• CPC Class Codes: A61F 2/2442 Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
• CPC Class Codes: A61F 2/246 Devices for obstructing a leak through a native valve in a closed condition

Abstract

Devices, systems and methods are provided for tissue approximation and repair at treatment sites. In particular, fixation devices are provided comprising a pair of elements each having a first end, a free end opposite the first end, and an engagement surface therebetween for engaging the tissue, the first ends being moveable between an open position wherein the free ends are spaced apart and a closed position wherein the free ends are closer together with the engagement surfaces generally facing each other. The fixation devices also include a locking mechanism coupled to the elements for locking the elements in place. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site.

Claims

1. An implantable fixation device for engaging cardiac tissue comprising:

a pair of elements each having a first end, a free end opposite the first end, and an engagement surface therebetween for engaging the tissue, the first ends being moveable between an open position wherein the free ends are spaced apart and a closed position wherein the free ends are closer together with the engagement surfaces generally facing each other, wherein the pair of elements in the closed position are adapted to reduce retrograde blood flow across the engaged tissue;

a locking mechanism coupled to the elements for locking the elements in place along a continuum of positions between the open position and the closed position;

a moveable stud pivotably coupled to both the elements wherein movement of the stud moves both the elements between the positions, the locking mechanism comprising at least one wedging element for frictionally engaging the stud to restrict movement thereof,

the at least one wedging element comprising a binding plate having a first end, a second end and a portion therebetween shaped to engage the stud, the binding plate positioned so that the portion is disposed near the stud; and

an unlocking mechanism for disengaging the locking mechanism, wherein the unlocking mechanism comprises a harness, the harness adapted to move the second end while the first end remains substantially stationary so as to reduce frictional engagement of the at least partially surrounding portion with the stud.

2. A fixation device as in claim 1, further comprising an unlocking mechanism for disengaging the locking mechanism so the elements are moveable.

3. A fixation device as in claim 1, wherein the portion shaped to engage the stud at least partially surrounds the stud, the binding plate positioned so that the portion at least partially surrounds the stud.

4. A fixation device as in claim 3, wherein the portion shaped to at least partially surround the stud comprises an aperture, the binding plate positioned so that the stud passes through the aperture.

5. A fixation device as in claim 4, wherein the locking mechanism further comprises a spring which forces the aperture against the stud to restrict movement of the stud through the aperture.

6. A fixation device as in claim 1, wherein the at least one wedging element comprises at least one cam, the at least one cam pivotable to frictionally engage the stud to restrict movement thereof.

7. A fixation device as in claim 6, wherein the at least one cam has an inward surface engageable with the stud and an outward surface connected with a spring which forces the inward surface against the stud to restrict movement of the stud.

8. A fixation device as in claim 7, further comprising an unlocking mechanism for disengaging the locking mechanism, wherein the unlocking mechanism comprises at least one actuator attached to a pivot point on each of the at least one cams, the at least one actuator adapted to pivot the at least one cam about its pivot point to reduce frictional engagement of the inner surface with the stud.

9. A fixation device as in claim 6, wherein the at least one cam comprises two cams, each cam disposed on opposite sides of the stud.

10. A fixation device as in claim 2, wherein the unlocking mechanism comprises a lock line operably coupled with the harness such that an upwards force in the lock line actuates the harness so as to move the second end.