System and method for detecting an involuntary muscle movement disorder

• US 7,616,988 B2
• Filed: 09/13/2004
• Issued: 11/10/2009
• Est. Priority Date: 09/18/2003
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Stahmann, Jeffrey E., Hartley, Jesse W., Lee, Kent, Ni, Quan
• Primary Examiner(s): Hindenburg; Max
• Assistant Examiner(s): Szmal; Brian
• Application Number:
  US10/939,639
• Publication Number:
  US 20050080463A1
• Time in Patent Office: 1,884 Days
• Field of Search: 600/300, 600/301, 600/392, 600/483, 600/523, 600/534, 600/546, 600/554, 600/587, 600/595, 600/529, 600/484, 600/501, 600/590, 607/2, 607/72, 607/48, 607/17, 607/42, 607/45
• US Class Current: 600/546
• CPC Class Codes: A61B 2505/05 Surgical care
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/395 Details of stimulation, e.g. nerve stimulation to elicit EMG response
• CPC Class Codes: A61B 5/4806 Sleep evaluation A61B5/4821 takes precedence; devices for inducing sleep A61M21/02
• CPC Class Codes: A61B 5/4809 Sleep detection, i.e. determining whether a subject is asleep or not
• CPC Class Codes: A61B 5/4812 Detecting sleep stages or cycles
• CPC Class Codes: A61B 5/6869 Heart
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance

Abstract

Methods and systems are directed to evaluating a pathological condition and involve acquiring muscle movement signals, such as electromyogram (EMG) or accelerometer signals, and detecting the presence of the pathological condition. Methods and systems also provide for detecting sleep-related involuntary muscle disorders and non sleep-related involuntary muscle disorders using muscle movement signals. Drug therapy, transcutaneous electric nerve stimulation therapy, or other therapy may be delivered to treat a detected or diagnosed involuntary muscle disorder.

Claims

1. A method of evaluating a pathological condition of a patient, comprising:

sensing muscle movement signals;

implantably storing sensed muscle movement data indicative of the sensed muscle movement signals;

implantably analyzing the stored muscle movement data and detecting a presence of an involuntary muscle movement disorder using the stored muscle movement data;

detecting whether the patient is asleep;

providing a first therapy to treat the involuntary muscle movement disorder in response to a determination that the patient is asleep; and

withholding the first therapy in response to a determination that the patient is not asleep.

2. The method of claim 1, wherein the sensing is performed at least in part internally of the patient.

3. The method of claim 1, wherein detecting the presence of the involuntary muscle movement disorder comprises detecting a sleep-related involuntary muscle movement disorder using the muscle movement signals.

4. The method of claim 1, wherein detecting the presence of the involuntary muscle movement disorder comprises detecting a non-sleep-related involuntary muscle movement disorder using the muscle movement signals.

5. The method of claim 1, wherein detecting the presence of the involuntary muscle movement disorder comprises detecting a disease using the muscle movement signals.

6. The method of claim 1, wherein detecting the presence of the involuntary muscle movement disorder comprises detecting a pathological syndrome using the muscle movement signals.

7. The method of claim 1, wherein the involuntary muscle movement disorder comprises a condition associated with one or more of bruxism, periodic limb movement disorder, restless leg syndrome, muscular dystrophy, muscle inflammation, pinched nerves, peripheral nerve damage, amyotrophic lateral sclerosis, myasthenia gravis, and disc herniation.

8. The method of claim 1, wherein sensing muscle movement signals comprises acquiring at least one of accelerometer data and electromyogram signals.

9. The method of claim 1, wherein information associated with the detected involuntary muscle movement disorder is at least one of, trended, communicated, displayed, or printed.

10. The method of claim 1, further comprising communicating one or both of the sensed muscle movement signals and information associated with the detected involuntary muscle movement disorder to a processing system external of the patient.

11. The method of claim 1, further comprising communicating one or both of the sensed muscle movement signals and information associated with the detected involuntary muscle movement disorder to a processing system internal of the patient.

12. The method of claim 1, wherein sensing the muscle movement signals comprises sensing at least some of the muscle movement signals from one or more intramuscular locations.

13. The method of claim 1, further comprising detecting one or more sleep stages using the muscle movement signals.

14. The method of claim 1, wherein the providing comprises at least one of delivering and controlling the therapy based on one or both of the muscle movement signals and the detected involuntary muscle movement disorder.

15. The method of claim 14, wherein the therapy comprises an internal therapy.

16. The method of claim 1, wherein the providing comprises at least one of delivering and controlling a transcutaneous electric nerve stimulation therapy based on one or both of the muscle movement signals and the detected involuntary muscle movement disorder.

17. A system for evaluating a pathological condition of a patient, comprising:

a sensor configured to sense movement of skeletal musculature;

a first detector coupled to the sensor;

a sleep detector that detects whether the patient is asleep;

implantable memory configured to store sensed data associated with an involuntary muscle movement disorder; and

an implantable processor coupled to the first detector and the sleep detector, the processor configured to analyze the stored data and to determine a presence of the involuntary muscle movement disorder; and

a therapy delivery system coupled to the processor and configured to;

provide a first therapy to treat the involuntary muscle movement disorder in response to a determination that the patient is asleep; and

withhold the first therapy in response to a determination that the patient is not asleep.

18. The system of claim 17, wherein one of the sensor and first detector comprises an implantable component.

19. The system of claim 17, wherein each of the sensor and first detector comprises an implantable component.

20. The system of claim 17, wherein the sensor comprises one or both of an electromyogram (EMG) sensor and an accelerometer.

21. The system of claim 17, wherein the processor is configured to determine presence of a condition associated with one or more of bruxism, periodic limb movement disorder, restless leg syndrome, muscular dystrophy, muscle inflammation, pinched nerves, peripheral nerve damage, amyotrophic lateral sclerosis, myasthenia gravis, and disc herniation.

22. The system of claim 17, further comprising a communication interface coupled to the processor, the communication interface configured to effect connectivity between the processor and a patient-external processing system or network.

23. The system of claim 17, wherein the therapy delivery system comprises a patient-external component.

24. The system of claim 17, wherein the therapy delivery system comprises an implantable component.

25. The system of claim 17, wherein the therapy delivery system is configured to deliver at least one of a drug therapy and a transcutaneous electric nerve stimulation therapy.

26. The system of claim 17, wherein at least one of the sensor and the processor is a component of an implantable cardiac rhythm management device.

27. A system for evaluating a pathological condition of a patient, comprising:

means for sensing muscle movement signals;

means for detecting whether the patient is asleep;

a memory configured to store sensed muscle movement data indicative of the sensed muscle movement signals; and

means for implantably analyzing the stored muscle movement data and for detecting a presence of an involuntary muscle movement disorder using the stored muscle movement data; and

means for providing a first therapy to treat the involuntary muscle movement disorder in response to a determination that the patient is asleep, and for withholding the first therapy in response to a determination that the patient is not asleep.