Composite material for implantable device

• US 7,637,868 B2
• Filed: 01/11/2005
• Issued: 12/29/2009
• Est. Priority Date: 01/12/2004
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brister, Mark, Saint, Sean
• Primary Examiner(s): Getzow; Scott M
• Application Number:
  US11/034,343
• Publication Number:
  US 20050181012A1
• Time in Patent Office: 1,813 Days
• Field of Search: 600/300, 600309-316, 600345-365, 607/36
• US Class Current: 600/365
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61N 1/37512 Pacemakers
• CPC Class Codes: Y10T 29/49002 Electrical device making
• CPC Class Codes: Y10T 29/49018 with other electrical component

Abstract

Devices suitable for implantation in a body of a host and systems and methods for their manufacture are provided. The implantable devices include a composite material formed at least from a matrix material and hollow gas-filled beads. In preferred embodiments, the composite material includes a polymeric matrix mixed with hollow air-filled glass beads, which are mixed and cured to form at least a portion of the body of the implantable device. Implantable devices including this composite material have decreased weight and/or overall density as compared to implantable devices without the beads incorporated therein, which is believed to improve the acceptance and function of the implantable device in vivo. Additionally, implantable devices concerned with transmitting and receiving via RF are believed to achieve improved RF performance due to a reduced dielectric constant provided by the incorporation of beads within the composite material.

Claims

1. A device suitable for implantation in a body of a host, the device comprising a composite material comprising a matrix material and a plurality of hollow gas-filled beads, wherein a dielectric constant of the composite material is less than a dielectric constant of the matrix material, the device further comprising an antenna that is configured for wireless communication and that is substantially encapsulated by the composite material, and wherein the composite material is configured to enhance tuning of the antenna.

2. The device of claim 1, wherein the beads are glass beads.

3. The device of claim 1, wherein the matrix material comprises a polymeric material.

4. The device of claim 3, wherein the polymeric material comprises an epoxy.

5. The device of claim 1, wherein the device comprises a body that is at least partially formed by mixing the matrix material and the hollow gas-filled beads to form a mixture, and curing the mixture.

6. The device of claim 1, wherein a diameter of at least a portion of the beads is from about 0.001 mm to about 3 mm.

7. The device of claim 1, wherein a diameter of at least a portion of the beads is about 1 mm or less.

8. The device of claim 1, further comprising an antenna for radiating or receiving an RF transmission.

9. The device of claim 8, wherein the composite material is proximal to the antenna or adjacent to the antenna.

10. The device of claim 1, wherein a weight percentage of the gas-filled beads is less than or equal to about 20% of composite material weight.

11. The device of claim 1, wherein a weight percentage of the gas-filled beads is less than or equal to about 15% of composite material weight.

12. The device of claim 1, wherein a weight percentage of the gas-filled beads is less than or equal to about 10% of composite material weight.

13. The device of claim 1, wherein a weight percentage of the gas-filled beads is less than or equal to about 5% of composite material weight.

14. A device suitable for implantation in a body of a host, the device comprising a composite material comprising a matrix material and a plurality of hollow gas-filled beads and further comprising an antenna for radiating or receiving an RF transmission, wherein the antenna is substantially encapsulated by the composite material, and wherein the composite material is configured to enhance tuning of the antenna.

15. The device of claim 14, wherein the composite material is proximal to the antenna or adjacent to the antenna.

16. The device of claim 14, wherein the beads are glass beads.

17. The device of claim 14, wherein the matrix material comprises a polymeric material.

18. The device of claim 17, wherein the polymeric material comprises an epoxy.

19. The device of claim 14, wherein the device comprises a body that is at least partially formed by mixing the matrix material and the hollow gas-filled beads to form a mixture, and curing the mixture.

20. The device of claim 14, wherein a diameter of at least a portion of the beads is from about 0.001 mm to about 3 mm.

21. The device of claim 14, wherein a diameter of at least a portion of the beads is about 1 mm or less.

22. A device suitable for implantation in a host, the device comprising electronics having an antenna for radiating or receiving an RF transmission and further comprising a body that substantially encapsulates the antenna, wherein the overall density of the device is about 1 g/cm³, and wherein the body is formed of a composite material configured to enhance tuning of the antenna.

23. The device of claim 22, wherein the body is formed from a composite material comprising a matrix material and a plurality of hollow gas-filled beads.

24. The device of claim 23, wherein the composite material has an overall density of less than about 1 g/cm³.

25. The device of claim 22, wherein the device is configured to measure glucose.

26. The device of claim 25, wherein the device is a wholly implantable glucose sensor configured for implantation in a subcutaneous tissue of a host.