Dosage forms of bisphosphonates

  • US 7,645,459 B2
  • Filed: 04/15/2005
  • Issued: 01/12/2010
  • Est. Priority Date: 05/24/2004
  • Status: Active Grant
First Claim
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1. An oral dosage form having pharmaceutically effective absorption comprising:

  • (a) from about 1 mg to about 500 mg of a bisphosphonate which is selected from the group consisting of risedronate and acids, salts, and esters thereof;

    (b) from about 10 mg to about 500 mg of EDTA; and

    (c) a delayed release mechanism to deliver the bisphosphonate and the EDTA in the lower gastrointestinal tract.

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