Treatment of reproductive endocrine disorders by vagus nerve stimulation
First Claim
Patent Images
1. A method of treating a reproductive disorder in a patient, comprising:
- coupling at least one electrode to at least one portion of a cranial nerve of the patient, wherein said cranial nerve is selected from the group consisting of a vagus nerve, a trigeminal nerve, an accessory nerve, or a hypoglossal nerve; and
applying an electrical signal to said cranial nerve using said electrode to treat said reproductive disorder, wherein treating said reproductive disorder comprises treating a disorder selected from the group consisting of infertility and amenorrhea.
7 Assignments
0 Petitions
Accused Products
Abstract
I disclose a method of treating a reproductive endocrine disorder in a patient, including coupling at least one electrode to at least one portion of a cranial nerve of the patient; and applying an electrical signal to said cranial nerve using said electrode to treat said reproductive endocrine disorder. Among the reproductive endocrine disorders which may be treated by the method are gonadal dysgenesis, hypogonadism, hypergonadism, delayed puberty, amenorrhea, infertility, premature menopause, and polycystic ovarian disease.
298 Citations
22 Claims
-
1. A method of treating a reproductive disorder in a patient, comprising:
-
coupling at least one electrode to at least one portion of a cranial nerve of the patient, wherein said cranial nerve is selected from the group consisting of a vagus nerve, a trigeminal nerve, an accessory nerve, or a hypoglossal nerve; and applying an electrical signal to said cranial nerve using said electrode to treat said reproductive disorder, wherein treating said reproductive disorder comprises treating a disorder selected from the group consisting of infertility and amenorrhea. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
-
-
12. A method of treating a reproductive endocrine disorder in a patient, comprising:
-
coupling at least one electrode to at least a portion of a cranial nerve of the patient, wherein said cranial nerve is selected from the group consisting of a vagus nerve, a trigeminal nerve, an accessory nerve, or a hypoglossal nerve; receiving a signal indicative of a symptom of the reproductive endocrine disorder; and applying an electrical signal to said cranial nerve using said electrode to treat said reproductive endocrine disorder in response to receiving said signal indicative of said symptom, wherein applying said electrical signal comprises applying said electrical signal in synchronization with at least one endogenous endocrine cycle. - View Dependent Claims (13, 14, 15, 16, 17, 18)
-
-
19. An implantable medical device system, comprising:
-
an electrode adapted to be coupled to a cranial nerve of a patient, wherein said cranial nerve is selected from the group consisting of a vagus nerve, a trigeminal nerve, an accessory nerve, or a hypoglossal nerve, and an implantable medical device for treating at least one reproductive disorder in a patient, comprising a controller for providing an electrical signal to the electrode, to treat said reproductive disorder, wherein treating said reproductive disorder comprises treating a disorder selected from the group consisting of and amenorrhea. - View Dependent Claims (20)
-
-
21. An implantable medical device system, comprising:
-
an electrode adapted to be coupled to a cranial nerve of a patient, wherein said cranial nerve is selected from the group consisting of a vagus nerve, a trigeminal nerve, an accessory nerve, or a hypoglossal nerve, and an implantable medical device for treating at least one reproductive disorder in a patient, comprising a controller for providing an electrical signal to the electrode for treating said reproductive endocrine disorder, wherein treating said reproductive disorder comprises treating a disorder selected from the group consisting of gonadal dysgenesis, hypogonadism, hypergonadism, delayed puberty, amenorrhea, infertility, premature menopause, polycystic ovarian syndrome, osteoporosis, hirsutism, and sarcopenia.
-
-
22. A method of treating a reproductive disorder in a patient, comprising:
-
coupling at least one electrode to at least one portion of a cranial nerve of the patient, wherein said cranial nerve is selected from the group consisting of a vagus nerve, a trigeminal nerve, an accessory nerve, or a hypoglossal nerve; and applying an electrical signal to said cranial nerve using said electrode to treat said reproductive disorder, wherein said electrical signal is applied in synchronization with said at least one endogenous endocrine cycle.
-
Specification