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Anesthesia drug monitor

  • US 7,693,697 B2
  • Filed: 10/11/2002
  • Issued: 04/06/2010
  • Est. Priority Date: 12/07/1999
  • Status: Active Grant
First Claim
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1. A system for modeling and predicting anesthesia drug effects on a patient, comprising:

  • a drug delivery system configured to deliver anesthesia drugs into the patient;

    a data stream device, in communication with the drug delivery systema simulator in communication with the drug delivery system, the simulator being configured to simulate drug administration effects and simulate infusion drugs by representing drug effects over time as a multi-dimensional visualization;

    a drug display monitor in communication with the data stream device and including;

    a data decoder receiving data from the data stream device;

    a dosage calculator receiving decoded data from the data decoder;

    a drug modeler and normalizer receiving calculated data from the data decoder;

    the drug modeler configured to determine a present and future probability of effectiveness of at least one drug introduced into the subject by the drug delivery system, wherein the present and future probabilities of drug effectiveness include a correlation of modeled pharamacokinetic data and modeled pharmacodynamic data; and

    a display generator that produces a display of;

    the present and future probabilities of effectiveness including predicted pharamacokinetic effect side concentrations depicted as a percent of a concentration value corresponding to a known pharmacodynamic probability of causing a particular bodily effect;

    a three-dimensional plot configured to provide a three-dimensional view of the effect of interactions of at least two anesthesia medicines;

    a bar graph and drug synergism is shown as an additional bar on the bar graph representing the additional effect on the patient due to drug interactions as the simulator simulates anesthetic drugs from the multi-dimensional visualizationa probability of effectiveness of at least one drug administered, including at least one of;

    a probability that a subject will be rendered unconscious by at least one drug having a sedative effect;

    a probability that a subject will not exhibit pain from laryngoscopy, incision, or post-operative recovery of surgery by at least one drug having and analgesic effect; and

    a probability that a subject will not exhibit a response to a train-of-four electrical muscle stimulation by at least one drug having a neuromuscular blocking effect, the probability of effectiveness determined based upon the model.

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