Optimised formulation of tobramycin for aerosolization

  • US 7,696,178 B2
  • Filed: 03/18/2005
  • Issued: 04/13/2010
  • Est. Priority Date: 07/02/2001
  • Status: Active Grant
First Claim
Patent Images

1. An aerosol formulation, comprising:

  • 75 mg/ml of tobramycin dissolved in an aqueous solution containing 0.45% w/v of sodium chloride;

    wherein the pH is between 4.5 and 5.5 and the osmolarity ranges between 250 and 450 mOsm/l, andsaid formulation is free of preservatives and anti-oxidants.

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