Self forming, thermodynamically stable liposomes and their applications

  • US 7,718,190 B2
  • Filed: 10/24/2006
  • Issued: 05/18/2010
  • Est. Priority Date: 12/20/2000
  • Status: Expired due to Term
First Claim
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1. A composition for the preparation of a liposome, said composition comprising:

  • an active compound, where the active compound is a protein, peptide, nucleic acid, agent for treating a neoplasm, agent for treating inflammation, agent for treating an infection, agent for treating a gasterointestinal disease, agent for treating an immunological disease, agent for treating a skin diseases or an eye disease, agent use in diagnosing disease, nutrient, agent for treating a blood disease, agent for treating a metabolic disease, agent for treating a cardiovascular disease, agent for treating a renal disease, agent for treating a genitourinary disease, agent for treating a respiratory disease or agent for treating a central nervous system disease; and

    one or more lipids selected from the group consisting of PEG-12 glycerol dioleate (GDO), PEG-12 glycerol dimyristate (GDM), PEG-23 glycerol dipalmitate (GDP), PEG-12 glycerol distearate (GDS), and PEG-23 GDS, where the number after “

    PEG”

    indicates the numbers of C2H4O subunits in the PEG chain.

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