Methods for diagnostic and therapeutic interventions in the peritoneal cavity

• US 7,721,742 B2
• Filed: 03/23/2001
• Issued: 05/25/2010
• Est. Priority Date: 03/24/2000
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Johns Hopkins University
• Inventors: Kalloo, Anthony Nicolas, Kantsevoy, Sergey Veniaminovich
• Primary Examiner(s): SHAY, DAVID M
• Application Number:
  US09/815,336
• Publication Number:
  US 20010049497A1
• Time in Patent Office: 3,350 Days
• Field of Search: 600102-104, 600/108, 600113-116, 600121-125, 600129-156, 604 27- 45, 604/500, 604/95.01, 604/95.03, 604/96.01, 60410101-10605, 604/121, 604/174, 604/50, 604/131, 604/139, 606 10- 13, 606 42- 52, 128/898
• US Class Current: 600/115
• CPC Class Codes: A61B 1/00082 Balloons
• CPC Class Codes: A61B 1/00087 Tools A61B17/00234 takes precedence
• CPC Class Codes: A61B 1/00135 Oversleeves mounted on the endoscope prior to insertion
• CPC Class Codes: A61B 1/00154 using guiding arrangements for insertion
• CPC Class Codes: A61B 1/01 Guiding arrangements therefore
• CPC Class Codes: A61B 1/018 for receiving instruments
• CPC Class Codes: A61B 1/2736 Gastroscopes
• CPC Class Codes: A61B 1/31 for the rectum, e.g. proctoscopes, sigmoidoscopes , colonoscopes
• CPC Class Codes: A61B 1/3132 for laparoscopy
• CPC Class Codes: A61B 1/32 Devices for opening or enlarging the visual field, e.g. of a tube of the body dilators A61M29/00
• CPC Class Codes: A61B 17/3478 Endoscopic needles, e.g. for infusion biopsy needles A61B10/0233; catheters with injection needles A61M25/0067
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00278 Transorgan operations, e.g. transgastric
• CPC Class Codes: A61B 2017/0034 adapted to be inserted through a working channel of an endoscope
• CPC Class Codes: A61B 2017/00973 pedal-operated
• CPC Class Codes: A61B 2017/0212 Cushions or pads, without holding arms, as tissue retainers, e.g. for retracting viscera
• CPC Class Codes: A61B 2017/0225 flexible, e.g. fabrics, meshes, or membranes
• CPC Class Codes: A61B 2017/22061 for spreading elements apart
• CPC Class Codes: A61B 2017/22069 Immobilising; Stabilising
• CPC Class Codes: A61B 2017/320048 : Balloon dissectors
• CPC Class Codes: A61B 2017/3425 : for internal organs, e.g. heart ports
• CPC Class Codes: A61B 2018/00494 : Stomach, intestines or bowel
• CPC Class Codes: A61B 2018/00595 : Cauterization
• CPC Class Codes: A61B 2018/00601 : Cutting
• CPC Class Codes: A61B 2018/00982 : combined with or comprising means for visual or photographic inspections inside the body, e.g. endoscopes
• CPC Class Codes: A61M 2025/0063 : having means, e.g. stylets, mandrils, rods or wires to reinforce or adjust temporarily the stiffness, column strength or pushability of catheters which are already inserted into the human body
• CPC Class Codes: A61M 2025/09008 : having a balloon
• CPC Class Codes: A61M 25/09 : Guide wires
• CPC Class Codes: A61M 25/1002 : characterised by balloon shape A61M25/1006, A61M25/1009 take precedence
• CPC Class Codes: A61M 25/1011 : Multiple balloon catheters

Abstract

A novel approach to diagnostic and therapeutic interventions in the peritoneal cavity is described. More specifically, a technique for accessing the peritoneal cavity via the wall of the digestive tract is provided so that examination of and/or a surgical procedure in the peritoneal cavity can be conducted via the wall of the digestive tract with the use of a flexible endoscope. As presently proposed, the technique is particularly adapted to transgastric peritoneoscopy. However, access in addition or in the alternative through the intestinal wall is contemplated and described as well. Transgastric and/or transintestinal peritoneoscopy will have an excellent cosmetic result as there are no incisions in the abdominal wall and no potential for visible post-surgical scars or hernias.

Claims

1. A method for accessing an interior of a cavity of a mammal, said method comprising:

positioning an elongated flexible conduit to extend from an exterior of the mammal through a natural orifice into and along at least a portion of the digestive tract to a target wall segment in the digestive tract;

forming an incision in said target wall segment;

advancing a distal end of said flexible conduit so that the distal end of said conduit extends through said wall;

after forming said incision and advancing the distal end of said flexible conduit through said wall, anchoring said distal end with respect to said wall;

advancing an endoscope through said conduit so that a distal end of said endoscope is disposed adjacent or distal to said distal end of said conduit;

viewing at least one of a tissue and an organ within said cavity;

releasing said anchor;

withdrawing said conduit and said endoscope through said wall; and

closing said incision,

further comprising, after said forming an incision and before said advancing said conduit, dilating said incision to facilitate passage of said conduit therethrough, wherein said dilating comprises dilating with an inflatable balloon.

2. A method as in claim 1, wherein an endoscope is disposed within said conduit during said positioning step and wherein said endoscope is manipulated to guide and direct said flexible conduit to said target wall segment.

3. A method as in claim 1, wherein said flexible conduit has a pair of anchoring balloons defined adjacent a distal end thereof, and wherein said anchoring comprises inflating said anchoring balloons so that a proximal said balloon is disposed within said digestive tract and a distal said balloon is disposed in the cavity, thereby to capture said wall therebetween.

4. A method as in claim 1, wherein said target wall segment is a portion of the stomach wall.

5. A method as in claim 1, wherein said positioning said flexible conduit comprises positioning said flexible conduit through the patient'"'"'s oral cavity and esophagus.

6. A method as in claim 1, wherein said method is performed in the absence of an incision in the abdominal wall.

7. A method as in claim 1, wherein said cavity is the peritoneal cavity.

8. A method as in claim 7, wherein a proximal end of said flexible conduit comprises a valve housing including a valve structure for defining a substantially air tight seal about said endoscope disposed therethrough and having a gas injection port, and wherein said method further comprises injecting a gas through said gas injection port so as to insufflate the peritoneal cavity after said anchoring step.

9. A method as in claim 1, further comprising, after said viewing, performing at least one endoscopic surgical procedure in said cavity.

10. A method as in claim 9, wherein said at least one surgical procedure comprises organ removal.

11. A method as in claim 1, wherein said closing comprises applying a mechanical fastener to at least partly close said incision.

12. A method as in claim 11, wherein said applying comprises applying a ligating clip to close at least a portion of said incision.

13. A method as in claim 12, wherein said applying comprises disposing a clip applicator through an accessory channel of said endoscope, engaging a clip disposed at a distal end of said clip applicator with tissue on each lateral side of said incision and actuating said clip so as to clamp said tissue and close said incision.

14. A method as in claim 1, wherein said forming comprises forming an incision with an endoscopic knife device.

15. A method as in claim 14, further comprising, after said forming, advancing a distal end of said endoscopic knife device through said incision.

16. A method as in claim 14, wherein said endoscopic knife device comprises a needle-knife, and wherein said forming comprises cutting said target wall segment with said needle-knife.

17. A method as in claim 16, wherein said endoscopic knife device is operatively coupled to an electrical source for heating said needle-knife and further comprising actuating said electrical source to heat said needle-knife.

18. A method as in claim 16, wherein said endoscopic knife device further comprises a conduit within which said needle-knife is disposed, and wherein said needle-knife can be selectively extended to project from a distal end of said conduit and selectively retracted so as to be disposed within said conduit and wherein said needle knife is mounted so as to be selectively removable through a proximal end of said needle-knife conduit and wherein said method further comprises, before said forming, extending said needle-knife to project from said distal end of said conduit, and after said forming step retracting said needle-knife.

19. A method as in claim 18, further comprising, after said forming, advancing the distal end of said endoscopic knife device through said incision.

20. A method as in claim 19, further comprising removing said needle-knife from said needle-knife conduit and feeding a guide wire through said needle-knife conduit.

21. A method as in claim 20, wherein said endoscopic knife device further comprises an inflatable balloon provided adjacent said distal end of said needle-knife conduit, and further comprising, after said advancing of said endoscopic knife device through said incision, inflating said inflatable balloon to dilate said incision.