Ischemia detection using heart sound timing
First Claim
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1. A device comprising:
- a heart sound sensor configured to produce a heart sound signal representative of a heart sound, the heart sound associated with mechanical cardiovascular activity of a heart of a subject; and
a signal analyzer circuit in electrical communication with the heart sound sensor, wherein the signal analyzer circuit is configured to;
establish a baseline value of a time interval between a first detected physiologic cardiovascular event and at least one second detected physiologic cardiovascular event, wherein the first and second detected events occur during a same cardiac cycle, wherein at least one of the first and second detected physiologic cardiovascular events includes a heart sound event detected using the heart sound signal, and wherein the other of the first and second detected physiologic cardiovascular events is associated with a different event;
after establishing the baseline, then monitor the time interval over a plurality of cardiac cycles; and
determine that an ischemic event occurred using information about how quickly a specified change from the established baseline time interval value occurs during the monitored plurality of cardiac cycles.
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Abstract
A system comprising a heart sound sensor to produce a heart sound signal representative of at least one heart sound. A signal analyzer circuit measures a baseline time interval between a first detected physiologic cardiovascular event and at least one second detected physiologic cardiovascular event. At least one of the first and second detected physiologic cardiovascular events includes a heart sound event obtained from the heart sound signal. The sensor analyzer circuit determines that an ischemic event occurred at least in part by detecting a specified measured subsequent change from the established baseline time interval. Other systems and methods are disclosed.
275 Citations
36 Claims
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1. A device comprising:
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a heart sound sensor configured to produce a heart sound signal representative of a heart sound, the heart sound associated with mechanical cardiovascular activity of a heart of a subject; and a signal analyzer circuit in electrical communication with the heart sound sensor, wherein the signal analyzer circuit is configured to; establish a baseline value of a time interval between a first detected physiologic cardiovascular event and at least one second detected physiologic cardiovascular event, wherein the first and second detected events occur during a same cardiac cycle, wherein at least one of the first and second detected physiologic cardiovascular events includes a heart sound event detected using the heart sound signal, and wherein the other of the first and second detected physiologic cardiovascular events is associated with a different event; after establishing the baseline, then monitor the time interval over a plurality of cardiac cycles; and determine that an ischemic event occurred using information about how quickly a specified change from the established baseline time interval value occurs during the monitored plurality of cardiac cycles. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method comprising:
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sensing a heart sound event using a heart sound sensor, the sensing including producing at least one heart sound signal representative of the heart sound event, the heart sound event associated with mechanical cardiovascular activity of a heart of a subject; using a signal analyzer circuit in communication with the heart sound sensor, establishing a baseline time interval between a first detected physiologic cardiovascular event and at least one second detected physiologic cardiovascular event, wherein the first and second detected physiologic cardiovascular events occur during a same cardiac cycle, wherein at least one of the first and second detected physiologic cardiovascular events includes a heart sound event detected using the heart sound signal, and wherein the other of the first and second detected physiologic cardiovascular events is associated with a different event; after establishing the baseline, then monitoring the time interval over a plurality of cardiac cycles; and determining, using the signal analyzer circuit, that an ischemic event occurred using information about how quickly a specified change from the established baseline time interval value occurs during the monitored plurality of cardiac cycles. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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Specification