Method and apparatus for circulatory valve repair

• US 7,758,596 B2
• Filed: 10/15/2002
• Issued: 07/20/2010
• Est. Priority Date: 06/27/1997
• Status: Expired due to Fees

• Current Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Original Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Inventors: Lemole, Gerald M., Umana, Juan P., Lotvin, Alan, Levin, Howard R., Allen, William, Oz, Mehmet C.
• Primary Examiner(s): Woo; Julian W
• Application Number:
  US09/950,163
• Publication Number:
  US 20040002719A1
• Time in Patent Office: 2,835 Days
• Field of Search: 606/153, 606/139, 606/142, 606/143, 606/205, 606/213, 606/215, 606/216, 606/217, 606/219, 606/220, 606/221, 606/157, 606/158, 606/210, 606/211, 227/175.1, 600/41
• US Class Current: 606/142
• CPC Class Codes: A61B 17/064 Surgical staples, i.e. penetrating the tissue
• CPC Class Codes: A61B 17/0644 penetrating the tissue, deformable to closed position
• CPC Class Codes: A61B 17/0686 having a forming anvil staying below the tissue during stapling
• CPC Class Codes: A61B 17/08 Wound clamps or clips, i.e. not or only partly penetrating the tissue suture bridges A61B17/0466; Devices for bringing together the edges of a wound
• CPC Class Codes: A61B 17/10 for applying or removing wound clamps, e.g. containing only one clamp or staple A61B17/076 takes precedence; containing multiple wound clamps A61B17/068; Wound clamp magazines containers, packaging elements or packages specially adapted for particular articles or with special means for dispensing contents B65D83/00, B65D85/00
• CPC Class Codes: A61B 17/122 Clamps or clips , e.g. for the umbilical cord for the vas deferens A61F6/206
• CPC Class Codes: A61B 17/1285 for minimally invasive surgery
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/0649 Coils or spirals
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation

Abstract

An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the leaflets. The apparatus is particularly useful for repairing mitral valves to cure mitral regurgitation.

Claims

1. A valve repair apparatus for percutaneously repairing a heart valve having leaflets, the valve repair apparatus comprising:

an insertion device having a control wire, a distal end configured for percutaneous insertion into a heart of a patient through a blood vessel, and a holder at the distal end in functional communication with the control wire; and

separate, first and second closure members releasably coupled to the holder at the distal end of the insertion device,

wherein the first and second closure members together comprise a separate, deployable fastener, releasable from the holder,

wherein the closure members each comprise a grasping surface for coapting the valve leaflets along a length of the valve leaflets when the grasping surfaces are placed about exterior surfaces of the valve leaflets,

wherein the control wire may be operated to fully close said grasping surfaces to engage the exterior surfaces of the valve leaflets to permit assessment of the valve repair and thereafter be operated to open the grasping surfaces to permit repositioning of the grasping surfaces of the fastener along its longitudinal axis prior to securing distal sections of the leaflets together or substantially adjacent to each other, and

wherein the first and second closure members are adjustably secured together or substantially adjacent to each other to secure valve leaflets together to repair the heart valve.

2. The valve repair apparatus of claim 1, wherein the deployable fastener is integral to the holder.

3. The valve repair apparatus of claim 1, wherein the holder comprises a pair of jaws configured to grasp the leaflets, at least one of the jaws being movable relative to the other jaw.

4. The valve repair apparatus of claim 3, wherein the deployable fastener is disposed on at least one of the jaws.

5. The valve repair apparatus of claim 1, wherein the deployable fastener comprises a clip.

6. The valve repair apparatus of claim 5, wherein the clip is U-shaped.

7. The valve repair apparatus of claim 1, further comprising a closure which fits over the grasping surfaces to secure the grasping surfaces to coapt the valve leaflets after the grasping surfaces are placed about the exterior of the leaflets of the valve.

8. The valve repair apparatus of claim 1, further comprising means for securing the first and second grasping surfaces together.

9. A valve repair apparatus for percutaneously repairing a heart valve having leaflets, the valve repair apparatus comprising:

an insertion device having a control wire, a distal end configured for percutaneous insertion into a heart of a patient through a blood vessel, and a holder at the distal end in functional communication with the control wire;

first and second closure members each releasably and separately coupled to the holder, and respectively comprising first and second grasping surfaces selectively moveable between a disengaged position to an engaged position by the control wire; and

means for coupling the first and second grasping surfaces together, wherein the first and second grasping surfaces and the coupling means together comprise a separate, deployable fastener releasable from the holder.