Capsule formulation of pirfenidone and pharmaceutically acceptable excipients

  • US 7,767,225 B2
  • Filed: 04/17/2009
  • Issued: 08/03/2010
  • Est. Priority Date: 09/22/2005
  • Status: Active Grant
First Claim
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1. A capsule comprising a pharmaceutical formulation of 5-methyl-1-phenyl-2-(1H)-pyridone, wherein said pharmaceutical formulation comprises 5-30% by weight of pharmaceutically acceptable excipients and 70-95% by weight of 5-methyl-1-phenyl-2-(1H)-pyridone, wherein said excipients comprise an effective amount of binder to increase the AUC of pirfenidone upon oral administration, as compared to a capsule comprising no excipients.

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