Low oxygen in vivo analyte sensor

  • US 7,771,352 B2
  • Filed: 05/01/2008
  • Issued: 08/10/2010
  • Est. Priority Date: 03/04/1997
  • Status: Expired due to Term
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First Claim
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1. A continuous glucose sensor system comprising:

  • an implantable body comprising an electrode configured to measure a glucose level in a host;

    a membrane disposed over the electrode, wherein the membrane comprises a resistance domain configured to limit transport of glucose to the electrode and an enzyme configured to catalyze a reaction of glucose and oxygen; and

    sensor electronics operably connected to the electrode and configured to measure a current produced by the electrode with substantial linearity at glucose concentrations of to about 400 mg/dL in a fluid with an oxygen concentration of less than about 0.3 mg/L.

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