Compositions and methods for enhancing corticosteroid delivery

  • US 7,794,738 B2
  • Filed: 01/24/2007
  • Issued: 09/14/2010
  • Est. Priority Date: 12/21/2001
  • Status: Active Grant
First Claim
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1. A method of delivering corticosteroids to skin comprising:

  • Topically applying a composition comprisingone or more corticosteroids with two or more penetration enhancers, and one or more of the group consisting of solvents and emulsifiers, wherein the penetration enhancers are present in ratio to a total of the penetration enhancers, and solvents and emulsifiers of at least about 0.90, and wherein the penetration enhancers comprise two or more of the group consisting of propylene glycol, diisopropyl adipate, dimethyl isosorbide, 1,2,6 hexanetriol, and benzyl alcohol, andwherein said composition does not include a monoglyceride of a C6-C10 medium chain fatty acid.

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