Compositions comprising nebivolol

  • US 7,803,838 B2
  • Filed: 05/31/2005
  • Issued: 09/28/2010
  • Est. Priority Date: 06/04/2004
  • Status: Active Grant
First Claim
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1. A composition comprising between about 0.125 mg to about 40 mg nebivolol or a pharmaceutically acceptable salt thereof and between about 1 mg to about 1200 mg of an angiotensin II receptor antagonist (ARB) selected from the group consisting of olmesartan, losartan, valsartan and pharmaceutically acceptable salts thereof wherein the composition provides a higher therapeutic index when administered to a patient having hypertension than either the corresponding amount of nebivolol or the ARB administered alone.

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