Localized fluid delivery having a porous applicator and methods for using the same

• US 7,815,596 B2
• Filed: 02/28/2002
• Issued: 10/19/2010
• Est. Priority Date: 02/28/2002
• Status: Active Grant

• Current Assignee: Cardinal Health Switzerland 515 GmbH (Cardinal Health, Inc.)
• Original Assignee: Cordis Corporation (Cardinal Health, Inc.)
• Inventors: Houle, Philip R, Riebman, Jerome B., Constantz, Brent R.
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): VU, QUYNH-NHU HOANG
• Application Number:
  US10/087,599
• Publication Number:
  US 20030163081A1
• Time in Patent Office: 3,155 Days
• Field of Search: 604/113, 604/500, 604 20- 22, 604506-508, 604/93.01, 604/264, 604/35, 604/115, 604/26
• US Class Current: 604/35
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 2017/22082 after introduction of a substance
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61B 2017/22097 Valve removal in veins
• CPC Class Codes: A61B 2017/22098 Decalcification of valves
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61M 1/84 Drainage tubes; Aspiration tips for negative pressure wound therapy A61M1/90; for surgical cutting instruments A61B17/32
• CPC Class Codes: A61M 2025/0004 having two or more concentrically arranged tubes for forming a concentric catheter system
• CPC Class Codes: A61M 2025/0036 with more than four lumina
• CPC Class Codes: A61M 2025/0039 characterized by lumina being arranged coaxially
• CPC Class Codes: A61M 2025/004 characterized by lumina being arranged circumferentially
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: A61M 2210/125 Heart
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00

Abstract

Fluid delivery devices having a porous applicator, as well as methods for using the same in the highly localized delivery of fluid to a target site, are provided. The subject devices have a porous applicator through which fluid must flow in order to contact the target delivery site. The subject devices find use in a variety of fluid delivery applications in which the localized delivery of a fluid to a target site is desired. Also provided are systems and kits that include the subject fluid delivery devices.

Claims

1. A device for locally contacting aortic valve leaflets with a demineralization fluid, the device comprising:

a central shaft;

three distinct fluid contact elements arranged around the central shaft, each fluid contacting element comprising a porous applicator affixed to an impermeable backing, wherein the impermeable backing is located only at proximal end of the porous applicator;

the distal ends of the fluid contacting elements being configured to fit snugly inside of the aortic sinus;

fluid delivery elements for delivering a demineralization fluid from a source to the porous applicators;

a shunt positioned within the central shaft and concentrically mounted therein for providing blood flow from the ventricle;

an aspiration lumen formed from a gap between the shunt and the central shaft; and

a valve occluder mounted to the central shaft, the valve occluder being configured to sit flush with the ventricular side of the aortic valve leaflets.