Analyte sensor

  • US 7,828,728 B2
  • Filed: 02/14/2007
  • Issued: 11/09/2010
  • Est. Priority Date: 07/25/2003
  • Status: Active Grant
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First Claim
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1. An implantable glucose sensor, the sensor comprising:

  • an electroactive surface configured for insertion into a host'"'"'s body; and

    a membrane system comprising a cell impermeable domain disposed between the electroactive surface and the host'"'"'s body when implanted, wherein the cell impermeable domain comprises a blend of a silicone polymer and a hydrophilic-hydrophobic polymer, wherein the blend is configured such that the cell impermeable domain allows transport of glucose therethrough, wherein the membrane system further comprises a diffusion resistance domain, and wherein glucose permeability of the cell impermeable domain is greater than a glucose permeability of the diffusion resistance domain.

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